Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 8/20 | 0.60 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.54 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.54 |
| ▸ | PLG | P00747 | 1/20 | 0.53 |
| ▸ | PLAU | P00749 | 1/20 | 0.53 |
| ▸ | ST14 | Q9Y5Y6 | 8/20 | 0.53 |
| ▸ | F2 | P00734 | 7/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.53 |
| ▸ | PRSS2 | P07478 | 6/20 | 0.53 |
| ▸ | PRSS3 | P35030 | 6/20 | 0.53 |
| ▸ | F10 | P00742 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8903303 | 0.84 | ITGB3 (0.56) | SMYD3ITGB3ITGA2BPLGPLAU | |
| SCHEMBL8715830 | 0.84 | ITGB3 (0.56) | SMYD3ITGB3ITGA2BPLGPLAU | |
| SCHEMBL25016846 | 0.81 | SMYD3 (0.73) | SMYD3PLAUST14F2PRSS1 | |
| SCHEMBL8712968 | 0.81 | PLG (0.51) | SMYD3ITGB3ITGA2BPLGPLAU | |
| SCHEMBL8903308 | 0.81 | PLG (0.51) | SMYD3ITGB3ITGA2BPLGPLAU | |
| SCHEMBL19710676 | 0.80 | SMYD3 (0.71) | SMYD3 | |
| SCHEMBL29908506 | 0.80 | SMYD3 (0.71) | SMYD3 | |
| SCHEMBL21490113 | 0.80 | SMYD3 (0.71) | SMYD3 | |
| SCHEMBL8904038 | 0.80 | PLG (0.47) | SMYD3ITGB3ITGA2BPLGPLAU | |
| SCHEMBL8712416 | 0.80 | PLG (0.47) | SMYD3ITGB3ITGA2BPLGPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3860636-B1 | MATRIPTASE 2 INHIBITORS AND USES THEREOF | DISC MEDICINE INC (US) | 2026-01-28 | — | — | EP | disclosed |