Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 2/20 | 0.51 |
| ▸ | PLAU | P00749 | 1/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 11/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 11/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.42 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.42 |
| ▸ | SMYD3 | Q9H7B4 | 4/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | SETD2 | Q9BYW2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8712968 | 1.00 | PLG (0.51) | PLGPLAUITGB3ITGA2BPRSS1 | |
| SCHEMBL8712416 | 0.89 | PLG (0.47) | PLGPLAUITGB3ITGA2BSMYD3 | |
| SCHEMBL8904038 | 0.89 | PLG (0.47) | PLGPLAUITGB3ITGA2BSMYD3 | |
| SCHEMBL8903303 | 0.89 | ITGB3 (0.56) | PLGPLAUITGB3ITGA2BPRSS1 | |
| SCHEMBL8715830 | 0.89 | ITGB3 (0.56) | PLGPLAUITGB3ITGA2BPRSS1 | |
| SCHEMBL32665962 | 0.81 | SMYD3 (0.60) | PLGPLAUITGB3ITGA2BPRSS1 | |
| SCHEMBL8715635 | 0.81 | ITGB3 (0.49) | PLGITGB3ITGA2BPRSS1PRSS2 | |
| SCHEMBL8905528 | 0.81 | ITGB3 (0.49) | PLGITGB3ITGA2BPRSS1PRSS2 | |
| SCHEMBL8904590 | 0.80 | TPSAB1 (0.53) | PLGITGB3ITGA2BPRSS1PRSS2 | |
| SCHEMBL8712942 | 0.80 | TPSAB1 (0.53) | PLGITGB3ITGA2BPRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5635527-A | ANTAGONIST OF PLATELET MEMBRANE GLYCOPROTEIN; TREATMENT OF THROMBOTIC DISEASES | THE GREEN CROSS CORPORATION (JP) | 1997-06-03 | — | — | US | disclosed |
| EP-0712844-A1 | NOVEL FUSED-RING CARBOXYLIC ACID COMPOUND OR SALT THEREOF, AND MEDICINAL USE THEREOF | THE GREEN CROSS CORPORATION (JP) | 1996-05-22 | — | — | EP | disclosed |