Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 15/20 | 0.56 |
| ▸ | ITGA2B | P08514 | 15/20 | 0.56 |
| ▸ | PLG | P00747 | 1/20 | 0.49 |
| ▸ | PLAU | P00749 | 1/20 | 0.49 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.42 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8715830 | 1.00 | ITGB3 (0.56) | ITGB3ITGA2BPLGPLAUSMYD3 | |
| SCHEMBL8903308 | 0.89 | PLG (0.51) | ITGB3ITGA2BPLGPLAUSMYD3 | |
| SCHEMBL8712968 | 0.89 | PLG (0.51) | ITGB3ITGA2BPLGPLAUSMYD3 | |
| SCHEMBL8904038 | 0.87 | PLG (0.47) | ITGB3ITGA2BPLGPLAUSMYD3 | |
| SCHEMBL8712416 | 0.87 | PLG (0.47) | ITGB3ITGA2BPLGPLAUSMYD3 | |
| SCHEMBL32665962 | 0.84 | SMYD3 (0.60) | ITGB3ITGA2BPLGPLAUSMYD3 | |
| SCHEMBL8904739 | 0.79 | ITGB3 (0.46) | ITGB3ITGA2BPLGF2F10 | |
| SCHEMBL8717391 | 0.79 | ITGB3 (0.46) | ITGB3ITGA2BPLGF2F10 | |
| SCHEMBL8904670 | 0.78 | F2 (0.55) | ITGB3ITGA2BF2 | |
| SCHEMBL8716704 | 0.78 | F2 (0.55) | ITGB3ITGA2BF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5635527-A | ANTAGONIST OF PLATELET MEMBRANE GLYCOPROTEIN; TREATMENT OF THROMBOTIC DISEASES | THE GREEN CROSS CORPORATION (JP) | 1997-06-03 | — | — | US | disclosed |
| EP-0712844-A1 | NOVEL FUSED-RING CARBOXYLIC ACID COMPOUND OR SALT THEREOF, AND MEDICINAL USE THEREOF | THE GREEN CROSS CORPORATION (JP) | 1996-05-22 | — | — | EP | disclosed |