Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.63 |
| ▸ | ATM | Q13315 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Clibucaine SCHEMBL248923 | 1.00 | ALDH1A1 (0.63) | ALDH1A1ATMMAPTPOLBSMN1; SMN2 | |
| Clibucaine SCHEMBL1815025 | 0.79 | HRH3 (0.58) | ALDH1A1ATMMAPTPOLBSMN1; SMN2 | |
| SCHEMBL30023041 | 0.73 | HPGD (0.59) | ALDH1A1ATMMAPTPOLBSMN1; SMN2 | |
| SCHEMBL497131 | 0.73 | POLB (0.72) | ALDH1A1ATMMAPTPOLBSMN1; SMN2 | |
| SCHEMBL9631346 | 0.72 | ALDH1A1 (0.54) | ALDH1A1MAPTPOLBSMN1; SMN2TDP1 | |
| SCHEMBL11578349 | 0.72 | HPGD (0.65) | ALDH1A1ATMMAPTPOLBSMN1; SMN2 | |
| SCHEMBL29387484 | 0.72 | ALDH1A1 (0.76) | ALDH1A1MAPTPOLBSMN1; SMN2TDP1 | |
| SCHEMBL4593633 | 0.71 | MAPT (0.77) | ALDH1A1ATMMAPTPOLBHTT | |
| SCHEMBL9180503 | 0.70 | HPGD (0.68) | ALDH1A1ATMMAPTPOLBSMN1; SMN2 | |
| SCHEMBL31590796 | 0.70 | HPGD (0.68) | ALDH1A1ATMMAPTPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4436552-B1 | GASTRO-RETENTIVE ORAL DOSAGE UNIT CONTAINING A LOCAL ANAESTHETIC | OREXA B V (NL) | 2026-02-04 | — | — | EP | claimed |