Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.77 |
| ▸ | NPC1 | O15118 | 2/20 | 0.68 |
| ▸ | RAB9A | P51151 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.67 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.67 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | GOT1 | P17174 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2093132 | 0.87 | MAPT (0.60) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL4390104 | 0.86 | MEN1 (0.62) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL28504510 | 0.84 | MAPT (0.68) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL10253279 | 0.81 | KMT2A (0.57) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL8394174 | 0.81 | RAB9A (0.68) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL702622 | 0.80 | TAS1R3 (1.00) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL9466466 | 0.80 | MAPT (0.58) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL702041 | 0.78 | TAS1R3 (1.00) | NPC1RAB9AMEN1KMT2ATAS1R3 | |
| SCHEMBL8747146 | 0.76 | MAPT (0.58) | MAPTMEN1KMT2ATAS1R3TAS1R1 | |
| SCHEMBL10596224 | 0.76 | MAPT (0.69) | MAPTNPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8212050-B2 | Amidine compounds and herbicides | NIPPON SODA CO., LTD. (JP) | 2012-07-03 | — | — | US | disclosed |
| US-20110301355-A1 | Amidine compounds and herbicides | NIPPON SODA CO., LTD. (JP) | 2011-12-08 | — | — | US | disclosed |
| EP-1911350-A1 | AMIDINE COMPOUND AND HERBICIDE | NIPPON SODA CO., LTD. (JP) | 2008-04-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110301355-A1 | Amidine compounds and herbicides | DDT, GATD3, PAM | MAPT 4226/4885NPC1 4594/4885RAB9A 1584/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.