Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | RORC | P51449 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL675647 | 0.78 | ALDH1A1 (0.63) | ALDH1A1MAPTPOLBCYP2C19KDM4E | |
| SCHEMBL28984808 | 0.77 | ALDH1A1 (0.62) | ALDH1A1MAPTPOLBSMN1; SMN2CYP2C19 | |
| SCHEMBL29387484 | 0.77 | ALDH1A1 (0.76) | ALDH1A1MAPTPOLBSMN1; SMN2TDP1 | |
| SCHEMBL17537292 | 0.77 | ALDH1A1 (0.62) | ALDH1A1MAPTPOLBSMN1; SMN2CYP2C19 | |
| SCHEMBL31136111 | 0.77 | ALDH1A1 (0.62) | ALDH1A1MAPTPOLBSMN1; SMN2CYP2C19 | |
| SCHEMBL830750 | 0.73 | KDM4E (0.74) | ALDH1A1POLBKDM4EMEN1KMT2A | |
| Clibucaine SCHEMBL32668857 | 0.72 | ALDH1A1 (0.63) | ALDH1A1MAPTPOLBSMN1; SMN2TDP1 | |
| Clibucaine SCHEMBL248923 | 0.72 | ALDH1A1 (0.63) | ALDH1A1MAPTPOLBSMN1; SMN2TDP1 | |
| SCHEMBL17755051 | 0.72 | KMT2A (0.57) | ALDH1A1MAPTPOLBSMN1; SMN2CYP2C19 | |
| SCHEMBL1285414 | 0.72 | MAPT (0.68) | ALDH1A1MAPTPOLBSMN1; SMN2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0220112-B1 | AROMATIC DERIVATIVES SUBSTITUTED BY AN (OMEGA-AMINO)-ALKANOL GROUP WITH AN ANTIMICROBIAL ACTIVITY, THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | ELF SANOFI (FR) | 1992-04-08 | — | — | EP | disclosed |
| EP-0220112-A2 | Aromatic derivatives substituted by an (omega-amino)-alkanol group with an antimicrobial activity, their preparation and compositions containing them | ELF SANOFI (FR) | 1987-04-29 | — | — | EP | disclosed |