SCHEMBL32669020

SCHEMBL32669020

NN1C(=O)c2cccc(CCCC=O)c2C1=O

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TYMS P04818 1/20 0.35
MPO P05164 1/20 0.34
ANPEP P15144 1/20 0.32
DPP4 P27487 1/20 0.32
NR1H2 P55055 1/20 0.32
NR1H3 Q13133 1/20 0.32
PRKCA P17252 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32668961 0.94 NR1H2 (0.36) TYMSMPOANPEPDPP4NR1H2
SCHEMBL31647607 0.78 DPP4 (0.41) TYMSMPOANPEPDPP4NR1H2
SCHEMBL3259476 0.74 GABRA1 (0.46) TYMSMPOANPEPDPP4
SCHEMBL22533625 0.70 DDB1 (0.61)
Hydrochloric Acid SCHEMBL17732252 0.68 KMT2A (0.46) NR1H3
SCHEMBL767500 0.68 HSPA1A (0.56) MPODPP4
SCHEMBL24421365 0.67 DPP4 (0.51) TYMSMPODPP4
SCHEMBL27360818 0.66 DPP4 (0.47) DPP4
SCHEMBL9450349 0.65 KDM4E (0.43) MPO
SCHEMBL7568712 0.65 DDB1 (0.43) MPODPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3725771-B1 ALK PROTEIN DEGRADATION AGENT AND ANTI-TUMOR APPLICATION THEREOF UNIV SHANGHAI TECHNOLOGY (CN) 2026-02-04 EP claimed