Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.35 |
| ▸ | IL2 | P60568 | 1/20 | 0.34 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.34 |
| ▸ | PRKAB2 | O43741 | 3/20 | 0.34 |
| ▸ | PRKAG1 | P54619 | 3/20 | 0.34 |
| ▸ | PRKAA2 | P54646 | 3/20 | 0.34 |
| ▸ | PRKAA1 | Q13131 | 3/20 | 0.34 |
| ▸ | PRKAG3 | Q9UGI9 | 3/20 | 0.34 |
| ▸ | PRKAG2 | Q9UGJ0 | 3/20 | 0.34 |
| ▸ | PRKAB1 | Q9Y478 | 3/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32669136 | 0.75 | NOTUM (0.56) | CA12CA1CA2CA9CYP2C9 | |
| SCHEMBL32669116 | 0.75 | NOTUM (0.40) | MAPK1NOTUMIL2MAP4K1PRKAB2 | |
| SCHEMBL29243088 | 0.72 | MAPT (0.48) | CA12CA1CA2CA9HDAC4 | |
| SCHEMBL29183406 | 0.72 | KMT2A (0.50) | CA12CA1CA2CA9CYP2C9 | |
| SCHEMBL5097743 | 0.72 | ALDH1A1 (0.51) | CA12CA1CA2CA9CYP2C9 | |
| SCHEMBL29243085 | 0.72 | NOTUM (0.51) | HDAC4MAPK1NOTUMMAPTNPC1 | |
| SCHEMBL1313699 | 0.72 | ALOX15 (0.53) | CYP2C9MAPK1NOTUMLMNATP53 | |
| SCHEMBL15062641 | 0.71 | KDM4E (0.47) | CA12CA1CA2CA9CYP2C9 | |
| SCHEMBL12274998 | 0.70 | ALDH1A1 (0.42) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL24323731 | 0.70 | F2R (0.38) | MAPK1KCNH2HRH3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260035358-A1 | WEE1 DEGRADING COMPOUNDS AND USES THEREOF | BRISTOL-MYERS SQUIBB COMPANY (US) | 2026-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260035358-A1 | WEE1 DEGRADING COMPOUNDS AND USES THEREOF | CRBN, WEE1, WEE2 | CA12 1486/4885CA1 1444/4885CA2 1805/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.