Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.44 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.44 |
| ▸ | MET | P08581 | 2/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | CLK1 | P49759 | 1/20 | 0.38 |
| ▸ | CLK2 | P49760 | 1/20 | 0.38 |
| ▸ | CLK3 | P49761 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 2/20 | 0.37 |
| ▸ | PIM1 | P11309 | 2/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.37 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18863211 | 0.82 | GRM2 (0.50) | GRM2PIK3CDPIK3CBPIK3CAMET | |
| SCHEMBL32669251 | 0.82 | PARP10 (0.51) | PARP1PARP10GRM5PIM1DYRK1A | |
| SCHEMBL11346836 | 0.81 | MEN1 (0.44) | GRM2METPARP1PARP10CLK1 | |
| SCHEMBL29531520 | 0.79 | PIK3CD (0.53) | GRM2PIK3CDPIK3CBPIK3CAMET | |
| SCHEMBL3532428 | 0.78 | GRM2 (0.46) | GRM2PIK3CDPIK3CBPIK3CAMET | |
| SCHEMBL31160537 | 0.78 | CLK4 (0.44) | GRM2PIK3CDPIK3CBPIK3CAMET | |
| SCHEMBL31160527 | 0.77 | GRM2 (0.47) | GRM2PIK3CDPIK3CBPIK3CAMET | |
| SCHEMBL32686478 | 0.75 | ALDH1A1 (0.37) | GRM2PIK3CDPIK3CBPIK3CAMET | |
| SCHEMBL32686477 | 0.74 | CLK1 (0.35) | GRM2PIK3CDPIK3CBPIK3CAMET | |
| SCHEMBL32686624 | 0.74 | CLK1 (0.38) | GRM2PIK3CDPIK3CBPIK3CAMET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024201248-A1 | COMPOUNDS AND METHODS FOR DEGRADING GSPT1 | PIN THERAPEUTICS, INC. (KR) | 2024-10-03 | — | — | WO | disclosed |