Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 9/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | PIKFYVE | Q9Y2I7 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 13/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32669225 | 0.83 | PIKFYVE (0.76) | GAAHPGDPIKFYVEMAPTALDH1A1 | |
| SCHEMBL32669254 | 0.83 | PIKFYVE (0.57) | GAAHPGDPIKFYVEMAPTALDH1A1 | |
| SCHEMBL32669248 | 0.76 | MAPT (0.71) | GAAHPGDPIKFYVEMAPTALDH1A1 | |
| SCHEMBL32669200 | 0.75 | GAA (0.59) | GAAHPGDMAPTALDH1A1HTT | |
| SCHEMBL32669325 | 0.74 | GAA (0.65) | GAAHPGDMAPTALDH1A1HTT | |
| SCHEMBL15890518 | 0.72 | MTOR (0.65) | GAAHPGDMAPTALDH1A1HTT | |
| SCHEMBL22737369 | 0.72 | GAA (0.59) | GAAHPGDMAPTALDH1A1HTT | |
| SCHEMBL24221970 | 0.71 | PIKFYVE (0.70) | GAAHPGDPIKFYVEMAPTALDH1A1 | |
| SCHEMBL31653615 | 0.71 | MAPT (0.80) | GAAHPGDMAPTALDH1A1HTT | |
| SCHEMBL26135108 | 0.71 | MAPT (0.80) | GAAHPGDMAPTALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260034141-A1 | METHODS AND COMPOSITIONS FOR TREATING MALIGNANT CANCERS | 6J BIOTECHNOLOGY HONG KONG LTD (HK) | 2026-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260034141-A1 | METHODS AND COMPOSITIONS FOR TREATING MALIGNANT CANCERS | MCL1, GLI1, BECN1 | GAA 1558/4885HPGD 3950/4885PIKFYVE 1479/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.