SCHEMBL32669200

SCHEMBL32669200

COc1cc(/C=N/Nc2nc(NCCc3ccccn3)nc(N3CCOCC3)n2)ccc1O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GAA P10253 6/20 0.59
▸ HPGD P15428 1/20 0.59
▸ MAPT P10636 11/20 0.54
▸ HTT P42858 2/20 0.53
▸ NPSR1 Q6W5P4 2/20 0.53
▸ PKM P14618 1/20 0.53
▸ ALDH1A1 P00352 5/20 0.51
▸ AKR1C3 P42330 1/20 0.49
▸ AKR1C1 Q04828 1/20 0.49
▸ CYP1A2 P05177 1/20 0.49
▸ CYP3A4 P08684 1/20 0.49
▸ CYP2C19 P33261 1/20 0.49
▸ RAB9A P51151 2/20 0.49
▸ MEN1 O00255 5/20 0.48
▸ KMT2A Q03164 5/20 0.48
▸ NPC1 O15118 1/20 0.48
▸ LMNA P02545 1/20 0.48
▸ KDM4E B2RXH2 1/20 0.48
▸ ALOX15 P16050 1/20 0.47
▸ PIK3CA P42336 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32669323 0.82 PIKFYVE (0.61) GAAMAPTHTTALDH1A1AKR1C3
SCHEMBL32669402 0.80 LMNA (0.49) GAAMAPTHTTALDH1A1AKR1C3
SCHEMBL32669339 0.78 PIK3CA (0.48) GAAMAPTHTTNPSR1PKM
SCHEMBL32669392 0.77 MAPT (0.47) GAAMAPTHTTNPSR1ALDH1A1
SCHEMBL32669325 0.76 GAA (0.65) GAAHPGDMAPTHTTNPSR1
SCHEMBL32669196 0.76 MAPT (0.67) GAAMAPTHTTNPSR1PKM
SCHEMBL22737369 0.75 GAA (0.59) GAAHPGDMAPTHTTNPSR1
SCHEMBL32669258 0.75 GAA (0.57) GAAHPGDMAPTHTTNPSR1
SCHEMBL425033 0.75 TYK2 (0.62) GAAHPGDMAPTHTTALDH1A1
SCHEMBL425032 0.75 TYK2 (0.62) GAAHPGDMAPTHTTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260034141-A1 METHODS AND COMPOSITIONS FOR TREATING MALIGNANT CANCERS 6J BIOTECHNOLOGY HONG KONG LTD (HK) 2026-02-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260034141-A1 METHODS AND COMPOSITIONS FOR TREATING MALIGNANT CANCERS MCL1, GLI1, BECN1 GAA 1558/4885HPGD 3950/4885MAPT 538/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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