Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 1/20 | 0.54 |
| ▸ | PPARG | P37231 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.43 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31155854 | 1.00 | PPARD (0.54) | PPARDPPARGMAPTCNR2CNR1 | |
| SCHEMBL31155865 | 0.96 | PPARD (0.53) | PPARDPPARGMAPTCNR2CNR1 | |
| SCHEMBL9119104 | 0.94 | PPARD (0.52) | PPARDPPARGMAPTCNR2LTB4R | |
| SCHEMBL31155910 | 0.94 | PPARD (0.54) | PPARDPPARGMAPTCNR2CNR1 | |
| SCHEMBL31155848 | 0.93 | PPARD (0.52) | PPARDPPARGMAPTLTB4RLTB4R2 | |
| SCHEMBL9119306 | 0.89 | PPARD (0.52) | PPARDPPARGMAPTCNR2CNR1 | |
| SCHEMBL9122597 | 0.88 | LTB4R (0.54) | PPARDPPARGCNR2CNR1LTB4R | |
| SCHEMBL3140786 | 0.87 | PPARD (0.55) | PPARDPPARGMAPTLTB4RLTB4R2 | |
| SCHEMBL6697391 | 0.85 | PPARD (0.50) | PPARDPPARGMAPT | |
| SCHEMBL15927987 | 0.84 | PPARG (0.60) | PPARDPPARGMAPTLTB4RLTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3546452-A1 | ANTIMALARIAL COMPOUNDS WITH FLEXIBLE SIDE-CHAINS | MMV Medicines for Malaria Venture (CH) | 2019-10-02 | — | — | EP | disclosed |
| EP-2194985-B1 | ANTIMALARIAL COMPOUNDS WITH FLEXIBLE SIDE-CHAINS | MEDICINES FOR MALARIA VENTURE MMV (CH) | 2019-02-20 | — | — | EP | disclosed |
| US-8530491-B2 | Antimalarial compounds with flexible side-chains | MEDICINES FOR MALARIA VENTURE (MMV) (CH) | 2013-09-10 | — | — | US | disclosed |
| EP-2194985-A1 | ANTIMALARIAL COMPOUNDS WITH FLEXIBLE SIDE-CHAINS | Medicines for Malaria Venture (CH) | 2010-06-16 | — | — | EP | disclosed |
| US-20090099220-A1 | ANTIMALARIAL COMPOUNDS WITH FLEXIBLE SIDE-CHAINS | MEDICINES FOR MALARIA VENTURE | 2009-04-16 | — | — | US | disclosed |
| WO-2009048957-A1 | ANTIMALARIAL COMPOUNDS WITH FLEXIBLE SIDE-CHAINS | MEDICINES FOR MALARIA VENTURE (CH) | 2009-04-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090099220-A1 | ANTIMALARIAL COMPOUNDS WITH FLEXIBLE SIDE-CHAINS | DHFR, FPGS, DHODH | PPARD 3477/4885PPARG 3029/4885MAPT 2302/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.