SCHEMBL32669339

SCHEMBL32669339

C(=N/Nc1nc(NCCc2ccccn2)nc(N2CCOCC2)n1)\c1cc2ccccc2[nH]1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PIK3CA P42336 5/20 0.48
▸ PIK3CB P42338 2/20 0.46
▸ PIK3CG P48736 2/20 0.46
▸ MAPT P10636 7/20 0.45
▸ KMT2A Q03164 6/20 0.45
▸ MEN1 O00255 5/20 0.45
▸ LMNA P02545 5/20 0.45
▸ GAA P10253 4/20 0.45
▸ NPSR1 Q6W5P4 3/20 0.45
▸ PIKFYVE Q9Y2I7 3/20 0.44
▸ CYP1A2 P05177 1/20 0.44
▸ CYP3A4 P08684 1/20 0.44
▸ CYP2C9 P11712 1/20 0.44
▸ CYP2C19 P33261 1/20 0.44
▸ ALDH1A1 P00352 3/20 0.43
▸ L3MBTL1 Q9Y468 2/20 0.43
▸ HTT P42858 2/20 0.42
▸ PKM P14618 1/20 0.42
▸ POLB P06746 1/20 0.42
▸ TDP1 Q9NUW8 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32669196 0.83 MAPT (0.67) PIK3CAPIK3CBPIK3CGMAPTKMT2A
SCHEMBL32669323 0.82 PIKFYVE (0.61) PIK3CAPIK3CBPIK3CGMAPTKMT2A
SCHEMBL32669402 0.80 LMNA (0.49) PIK3CAPIK3CBPIK3CGMAPTKMT2A
SCHEMBL32669392 0.79 MAPT (0.47) PIK3CAPIK3CBPIK3CGMAPTKMT2A
SCHEMBL32669200 0.78 GAA (0.59) PIK3CAPIK3CBPIK3CGMAPTKMT2A
SCHEMBL23345486 0.77 MAPT (0.69) MAPTKMT2AMEN1LMNAGAA
SCHEMBL32669211 0.75 MAPT (0.70) PIK3CAPIK3CBPIK3CGMAPTKMT2A
SCHEMBL1309950 0.74 PIK3CA (0.55) PIK3CAPIK3CBPIK3CGKMT2AMEN1
SCHEMBL32669448 0.74 PIKFYVE (0.64) PIK3CAPIK3CBPIK3CGMAPTKMT2A
SCHEMBL32669369 0.73 MAPT (0.58) PIK3CAMAPTKMT2AMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260034141-A1 METHODS AND COMPOSITIONS FOR TREATING MALIGNANT CANCERS 6J BIOTECHNOLOGY HONG KONG LTD (HK) 2026-02-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260034141-A1 METHODS AND COMPOSITIONS FOR TREATING MALIGNANT CANCERS MCL1, GLI1, BECN1 PIK3CA 762/4885PIK3CB 606/4885PIK3CG 773/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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