Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 2/20 | 0.47 |
| ▸ | MMP9 | P14780 | 2/20 | 0.46 |
| ▸ | MMP8 | P22894 | 2/20 | 0.46 |
| ▸ | FCER2 | P06734 | 3/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 2/20 | 0.41 |
| ▸ | MME | P08473 | 6/20 | 0.41 |
| ▸ | ACE | P12821 | 4/20 | 0.41 |
| ▸ | CPA1 | P15085 | 2/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8235025 | 0.92 | GHSR (0.49) | GHSRMMP9MMP8FCER2F2 | |
| SCHEMBL6320694 | 0.88 | MMP9 (0.56) | GHSRMMP9MMP8FCER2F2 | |
| SCHEMBL3266799 | 0.87 | MMP9 (0.45) | GHSRMMP9MMP8FCER2F2 | |
| SCHEMBL3266844 | 0.86 | GHSR (0.48) | GHSRMMP9MMP8FCER2F2 | |
| SCHEMBL6848992 | 0.86 | MMP9 (0.46) | GHSRMMP9MMP8FCER2F2 | |
| SCHEMBL3266812 | 0.85 | MMP9 (0.47) | GHSRMMP9MMP8FCER2F2 | |
| SCHEMBL6317992 | 0.85 | FCER2 (0.53) | GHSRMMP9MMP8FCER2F2 | |
| SCHEMBL4427112 | 0.85 | FCER2 (0.53) | GHSRMMP9MMP8FCER2F2 | |
| SCHEMBL4426088 | 0.85 | FCER2 (0.53) | GHSRMMP9MMP8FCER2F2 | |
| SCHEMBL8170611 | 0.84 | GHSR (0.54) | GHSRMMP9MMP8FCER2F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1047709-B1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK AS (DK) | 2004-11-03 | — | — | EP | claimed |
| EP-1506969-B1 | Compounds with growth hormone releasing properties | HELSINN THERAPEUTICS US INC (US) | 2010-06-09 | — | — | EP | disclosed |
| EP-1506969-A1 | Compounds with growth hormone releasing properties | NOVO NORDISK A/S (DK) | 2005-02-16 | — | — | EP | disclosed |
| EP-1047709-B1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK AS (DK) | 2004-11-03 | — | — | EP | disclosed |
| US-6083908-A | TREATING MEDICAL DISORDERS RESULTING FROM DEFICIENCY IN GROWTH HORMONE | NOVO NORDISK A/S (DK) | 2000-07-04 | — | — | US | disclosed |