SCHEMBL32669723

SCHEMBL32669723

Cc1ccc(F)c(CN(C)C(=O)/C(C#N)=C(\O)c2cc(C#N)c(O)c(C)c2F)c1

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.33
MEN1 O00255 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33
GALK1 P51570 1/20 0.33
KMT2A Q03164 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
RIPK1 Q13546 1/20 0.30
COMT P21964 1/20 0.30
FTO Q9C0B1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32669937 0.91 MEN1 (0.32) POLBMEN1ALDH1A1MAPTGALK1
SCHEMBL32669970 0.86 MEN1 (0.39) POLBMEN1ALDH1A1MAPTGALK1
SCHEMBL32669743 0.85 MEN1 (0.39) POLBMEN1ALDH1A1MAPTGALK1
SCHEMBL32669812 0.85 MEN1 (0.33) POLBMEN1ALDH1A1MAPTGALK1
SCHEMBL32670033 0.84 COMT (0.41) POLBMEN1ALDH1A1MAPTGALK1
SCHEMBL32669922 0.83 MEN1 (0.38) POLBMEN1ALDH1A1MAPTGALK1
SCHEMBL32669590 0.83 SCN9A (0.33) POLBMEN1ALDH1A1MAPTGALK1
SCHEMBL32669773 0.83 HSP90AA1 (0.33) POLBMEN1ALDH1A1MAPTGALK1
SCHEMBL32670105 0.82 ALDH1A1 (0.37) POLBMEN1ALDH1A1MAPTGALK1
SCHEMBL32670129 0.80 MEN1 (0.40) POLBMEN1ALDH1A1MAPTGALK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260035341-A1 FTO INHIBITORS RPXDS CO LTD (CN) 2026-02-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260035341-A1 FTO INHIBITORS FTO, LDLR, GPR119 POLB 3968/4885MEN1 3974/4885ALDH1A1 1334/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.