SCHEMBL32671098

SCHEMBL32671098

C[Si](C)(C)CCOCn1ncc2c(Cl)cc(Br)cc21

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ DGAT1 O75907 3/20 0.36
▸ TP53 P04637 1/20 0.33
▸ NPC1 O15118 1/20 0.31
▸ MAPT P10636 1/20 0.31
▸ PDE4D Q08499 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30706826 0.85 DGAT1 (0.33) DGAT1
SCHEMBL25366051 0.85 DGAT1 (0.45) DGAT1NPC1
SCHEMBL29493833 0.85 DGAT1 (0.45) DGAT1NPC1
SCHEMBL31460489 0.82 DGAT1 (0.34) DGAT1NPC1PDE4D
SCHEMBL15562504 0.80 MAPT (0.34) NPC1MAPT
SCHEMBL26694764 0.80 DGAT1 (0.35) DGAT1
SCHEMBL30709985 0.80 DGAT1 (0.35) DGAT1
SCHEMBL20604807 0.79 HSD17B10 (0.34) DGAT1NPC1MAPTPDE4D
SCHEMBL32671213 0.77 — —
SCHEMBL20535503 0.77 DGAT1 (0.36) DGAT1NPC1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260078119-A1 DEGRADER COMPOUNDS AND USES THEREOF BRISTOL MYERS SQUIBB CO (US) 2026-03-19 — — US disclosed
EP-4688771-A1 NOVEL FAK DEGRADER COMPOUNDS AND USES THEREOF Bristol-Myers Squibb Company (US) 2026-02-11 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260078119-A1 DEGRADER COMPOUNDS AND USES THEREOF CTTN, SRC, PTK2 DGAT1 4421/4885TP53 51/4885NPC1 2916/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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