SCHEMBL32672473

SCHEMBL32672473

C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(OC(=O)c1cccc([N+](=O)[O-])c1)C(=O)N(C)C

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NR3C1 P04150 14/20 0.55
▸ PGR P06401 5/20 0.55
▸ CYP3A4 P08684 4/20 0.55
▸ USP2 O75604 3/20 0.55
▸ LMNA P02545 2/20 0.55
▸ NR1I2 O75469 2/20 0.55
▸ MAPT P10636 2/20 0.55
▸ MLNR O43193 1/20 0.55
▸ ABCB11 O95342 1/20 0.55
▸ CYP3A5 P20815 1/20 0.55
▸ PPARG P37231 1/20 0.55
▸ SMN1; SMN2 Q16637 1/20 0.55
▸ NPSR1 Q6W5P4 1/20 0.55
▸ CYP2D6 P10635 1/20 0.55
▸ CYP2C9 P11712 1/20 0.55
▸ MMP1 P03956 9/20 0.54
▸ ADORA3 P0DMS8 1/20 0.54
▸ DRD2 P14416 1/20 0.54
▸ OPRD1 P41143 1/20 0.54
▸ MEN1 O00255 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32672321 0.92 NR3C1 (0.58) NR3C1PGRCYP3A4USP2LMNA
SCHEMBL32672362 0.90 NR3C1 (0.69) NR3C1PGRCYP3A4USP2LMNA
SCHEMBL32672492 0.88 NR3C1 (0.56) NR3C1PGRCYP3A4NR1I2MAPT
SCHEMBL11853853 0.81 NR3C1 (0.65) NR3C1PGRCYP3A4USP2LMNA
SCHEMBL11853850 0.81 NR3C1 (0.65) NR3C1PGRCYP3A4USP2LMNA
SCHEMBL32672459 0.81 NR3C1 (0.60) NR3C1PGRCYP3A4NR1I2MAPT
SCHEMBL11813494 0.81 NR3C1 (0.65) NR3C1PGRCYP3A4USP2LMNA
SCHEMBL11813496 0.81 NR3C1 (0.65) NR3C1PGRCYP3A4USP2LMNA
SCHEMBL30915304 0.80 NR3C1 (0.54) NR3C1PGRCYP3A4NR1I2MAPT
SCHEMBL32672423 0.80 NR3C1 (0.54) NR3C1PGRCYP3A4NR1I2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260041781-A1 NOVEL GLUCOCORTICOID RECEPTOR AGONISTS AND IMMUNOCONJUGATES THEREOF ADCENTRX THERAPEUTICS INC (US) 2026-02-12 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260041781-A1 NOVEL GLUCOCORTICOID RECEPTOR AGONISTS AND IMMUNOCONJUGATES THEREOF NR3C1, NR3C2, MC2R NR3C1 1/4885PGR 107/4885CYP3A4 755/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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