Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | ALPG | P10696 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3270795 | 0.89 | PPARD (0.43) | PPARDMEN1KMT2AMAPTALOX12 | |
| SCHEMBL3266067 | 0.89 | PPARD (0.55) | PPARDNPC1RAB9AMEN1KMT2A | |
| SCHEMBL3280957 | 0.88 | PPARD (0.44) | PPARDNPC1RAB9AMEN1KMT2A | |
| SCHEMBL657110 | 0.83 | PPARD (0.67) | PPARD | |
| SCHEMBL657109 | 0.83 | PPARD (0.67) | PPARD | |
| SCHEMBL3267255 | 0.81 | PPARD (0.51) | PPARDNPC1RAB9AKMT2AMAPT | |
| SCHEMBL3270793 | 0.77 | PPARD (0.44) | PPARDMEN1KMT2AMAPTKDM4E | |
| SCHEMBL3266065 | 0.77 | PPARD (0.57) | PPARDNPC1RAB9AMEN1KMT2A | |
| SCHEMBL3270787 | 0.77 | PPARD (0.44) | PPARDMEN1KMT2AMAPTKDM4E | |
| SCHEMBL5959436 | 0.77 | PPARD (0.74) | PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1558571-B1 | NOVEL COMPOUNDS USEFUL IN TREATING PPAR MEDIATED DISEASES | HIGH POINT PHARMACEUTICALS LLC (US) | 2010-06-02 | — | — | EP | claimed |