Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3264487 | 0.89 | FAAH (0.34) | HRH3KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL3232200 | 0.89 | FAAH (0.34) | HRH3KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL3266879 | 0.89 | FAAH (0.34) | HRH3KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL3264465 | 0.89 | FAAH (0.34) | HRH3KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL3267299 | 0.89 | HRH3 (0.37) | HRH3KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL3267163 | 0.85 | EPHX2 (0.37) | KDM4EALDH1A1MEN1KMT2AMTNR1B | |
| SCHEMBL3220898 | 0.84 | MTNR1B (0.39) | KDM4EALDH1A1MEN1KMT2AMTNR1B | |
| SCHEMBL3228839 | 0.84 | EPHX2 (0.43) | KDM4EALDH1A1MEN1KMT2AMTNR1B | |
| SCHEMBL690229 | 0.84 | EPHX2 (0.43) | KDM4EALDH1A1MEN1KMT2AMTNR1B | |
| SCHEMBL689276 | 0.84 | EPHX2 (0.43) | KDM4EALDH1A1MEN1KMT2AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010026096-A1 | 7-(PIPERAZINE-1-YMETHYL)-1H-INDOLE-2-CARBOXYLIC ACID (PHENYL)-AMIDE DERIVATIVES AND ALLIED COMPOUNDS AS P38 MAP KINASE INHIBITORS FOR THE TREATMENT OF RESPIRATORY DISEASES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-03-11 | — | — | WO | claimed |
| WO-2010026096-A1 | 7-(PIPERAZINE-1-YMETHYL)-1H-INDOLE-2-CARBOXYLIC ACID (PHENYL)-AMIDE DERIVATIVES AND ALLIED COMPOUNDS AS P38 MAP KINASE INHIBITORS FOR THE TREATMENT OF RESPIRATORY DISEASES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-03-11 | — | — | WO | disclosed |