Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 8/20 | 0.45 |
| ▸ | CNR2 | P34972 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 2/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3267515 | 0.79 | CNR1 (0.49) | CNR1CNR2KMT2A | |
| SCHEMBL3268899 | 0.78 | CNR1 (0.48) | CNR1CNR2KMT2ACYP3A4 | |
| SCHEMBL3267028 | 0.78 | CNR1 (0.51) | CNR1CNR2KMT2A | |
| SCHEMBL3366114 | 0.69 | CNR1 (0.65) | CNR1CNR2KMT2AHTT | |
| SCHEMBL3367684 | 0.69 | CNR1 (0.65) | CNR1CNR2KMT2AHTT | |
| SCHEMBL4480277 | 0.69 | ALDH1A1 (0.51) | CNR1CNR2ALDH1A1RXFP1MAPT | |
| SCHEMBL11081773 | 0.69 | MAPT (0.58) | ALDH1A1MAPK1MEN1KMT2AMAPT | |
| SCHEMBL3814385 | 0.68 | DPP4 (0.40) | ALDH1A1RXFP1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL18668950 | 0.66 | CES2 (0.67) | ALDH1A1ADRA1DADRA1AADRA1B | |
| SCHEMBL3729290 | 0.66 | GRM5 (0.54) | ALDH1A1MEN1KMT2AHTTGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7781471-B2 | Diaryl triazolmethylamine derivatives, preparation and therapeutic use thereof | SANOFI-AVENTIS (FR) | 2010-08-24 | — | — | US | disclosed |
| EP-1966167-B1 | DIARYLTRIAZOLMETHYLAMINE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI AVENTIS (FR) | 2010-06-16 | — | — | EP | disclosed |
| US-20080293794-A1 | DIARYLTRIAZOLMETHYLAMINE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2008-11-27 | — | — | US | disclosed |
| EP-1966167-A1 | DIARYLTRIAZOLMETHYLAMINE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF | sanofi-aventis (FR) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007068814-A1 | DIARYLTRIAZOLMETHYLAMINE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2007-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293794-A1 | DIARYLTRIAZOLMETHYLAMINE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF | LTB4R2, LTB4R, CYSLTR1 | CNR1 31/4885CNR2 15/4885ALDH1A1 565/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.