Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3267076 | 0.95 | ACACB (0.32) | ACACBACACA | |
| SCHEMBL3268479 | 0.91 | SPR (0.31) | — | |
| SCHEMBL3273870 | 0.89 | — | — | |
| SCHEMBL2951808 | 0.83 | PKM (0.31) | — | |
| SCHEMBL3741418 | 0.80 | BACE1 (0.31) | ACACBACACA | |
| SCHEMBL6290225 | 0.78 | ACACB (0.43) | ACACBACACA | |
| SCHEMBL730629 | 0.78 | ACACB (0.46) | ACACBACACA | |
| SCHEMBL2524812 | 0.77 | — | — | |
| SCHEMBL12496896 | 0.76 | PDE7A (0.40) | — | |
| SCHEMBL13039832 | 0.76 | ACACB (0.48) | ACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2195290-B1 | HALOGEN ALKOXY SPIROCYCLIC TETRAMIC AND TETRONIC ACID DERIVATIVES | BAYER IP GMBH (DE) | 2015-03-11 | — | — | EP | disclosed |
| US-8435549-B2 | Halogen alkoxy spirocyclic tetramic and tetronic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2013-05-07 | — | — | US | disclosed |
| US-20100279873-A1 | Halogen Alkoxy Spirocyclic Tetramic and Tetronic Acid Derivatives | BAYER CROPSCIENCE AG (DE) | 2010-11-04 | — | — | US | disclosed |
| EP-2195290-A1 | HALOGEN ALKOXY SPIROCYCLIC TETRAMIC AND TETRONIC ACID DERIVATIVES | Bayer CropScience AG (DE) | 2010-06-16 | — | — | EP | disclosed |
| EP-2045240-A1 | Halogen alkoxy spirocyclic tetram and tetron acid derivatives | Bayer CropScience AG (DE) | 2009-04-08 | — | — | EP | disclosed |
| EP-2045240-A1 | Halogen alkoxy spirocyclic tetram and tetron acid derivatives | Bayer CropScience AG (DE) | 2009-04-08 | — | — | EP | disclosed |
| WO-2009039975-A1 | HALOGEN ALKOXY SPIROCYCLIC TETRAMIC AND TETRONIC ACID DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2009-04-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100279873-A1 | Halogen Alkoxy Spirocyclic Tetramic and Tetronic Acid Derivatives | KCNA5, KCNH1, KCNQ5 | ACACB 1475/4885ACACA 622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.