Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 6/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.54 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10458447 | 0.84 | KDM4E (0.72) | CYP1A2KDM4EMEN1KMT2AMAPT | |
| SCHEMBL11449284 | 0.79 | CYP1A2 (0.65) | CYP1A2KDM4EMEN1KMT2AMAPT | |
| SCHEMBL8830517 | 0.77 | SMN1; SMN2 (0.73) | CYP1A2KDM4EMEN1KMT2AMAPT | |
| SCHEMBL8421117 | 0.77 | CYP1A2 (0.62) | CYP1A2KDM4EMEN1KMT2AMAPT | |
| SCHEMBL9036644 | 0.77 | CYP1A2 (0.68) | CYP1A2KDM4EMEN1KMT2AMAPT | |
| SCHEMBL2877144 | 0.77 | CYP1A2 (0.56) | CYP1A2KDM4EMEN1KMT2AMAPT | |
| SCHEMBL6859262 | 0.76 | CYP1A2 (0.64) | CYP1A2KDM4EMEN1KMT2AMAPT | |
| SCHEMBL1700678 | 0.76 | MEN1 (0.87) | CYP1A2KDM4EMEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL5119113 | 0.76 | CYP1A2 (0.66) | CYP1A2KDM4EMEN1KMT2AMAPT | |
| SCHEMBL3264574 | 0.75 | SMN1; SMN2 (0.64) | KDM4EMEN1KMT2AMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1776347-B1 | SULPHONAMIDE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI AVENTIS (FR) | 2010-05-26 | — | — | EP | disclosed |