Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKLR | P30613 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.48 |
| ▸ | TNF | P01375 | 4/20 | 0.44 |
| ▸ | NOD2 | Q9HC29 | 4/20 | 0.44 |
| ▸ | NOD1 | Q9Y239 | 4/20 | 0.44 |
| ▸ | CA12 | O43570 | 4/20 | 0.43 |
| ▸ | CA1 | P00915 | 4/20 | 0.43 |
| ▸ | CA2 | P00918 | 4/20 | 0.43 |
| ▸ | CA4 | P22748 | 4/20 | 0.43 |
| ▸ | CA6 | P23280 | 4/20 | 0.43 |
| ▸ | CA7 | P43166 | 4/20 | 0.43 |
| ▸ | CA9 | Q16790 | 4/20 | 0.43 |
| ▸ | CA13 | Q8N1Q1 | 4/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.43 |
| ▸ | CA3 | P07451 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32673967 | 0.86 | THRB (0.48) | PKLRTHRBNOTUMTNFNOD2 | |
| SCHEMBL26656390 | 0.86 | NOTUM (0.48) | PKLRTHRBNOTUMTNFNOD2 | |
| SCHEMBL26656315 | 0.85 | NOTUM (0.47) | PKLRTHRBNOTUMTNFNOD2 | |
| SCHEMBL32673839 | 0.77 | NOTUM (0.56) | PKLRTHRBNOTUMTNFNOD2 | |
| SCHEMBL32673573 | 0.75 | NOTUM (0.47) | PKLRTHRBNOTUMTNFNOD2 | |
| SCHEMBL26656423 | 0.72 | FAAH (0.41) | TNFNOD2KMT2AMEN1ALDH1A1 | |
| SCHEMBL26079156 | 0.71 | NOTUM (0.64) | PKLRTHRBNOTUMTNFNOD2 | |
| SCHEMBL32673781 | 0.70 | TNF (0.38) | THRBTNFNOD2NOD1KMT2A | |
| SCHEMBL32673959 | 0.70 | TNF (0.38) | THRBTNFNOD2NOD1KMT2A | |
| SCHEMBL5798751 | 0.70 | NOTUM (0.62) | PKLRTHRBNOTUMTNFNOD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260042748-A1 | AZETIDINE COMPOUNDS FOR TREATMENT OF HSV | ASSEMBLY BIOSCIENCES INC (US) | 2026-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260042748-A1 | AZETIDINE COMPOUNDS FOR TREATMENT OF HSV | CXCR1, ZC3HAV1L, ZC3HAV1 | PKLR 4423/4885THRB 3232/4885NOTUM 4724/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.