Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.31 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.33 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3266632 | 0.88 | — | — | |
| Hydrochloric Acid SCHEMBL3271567 | 0.85 | KDM4E (0.32) | ALDH1A1CYP1A2HPGDCYP2C19KDM4E | |
| Hydrochloric Acid SCHEMBL3267591 | 0.85 | NPC1 (0.32) | ALDH1A1CYP1A2HPGDCYP2C19KDM4E | |
| Hydrochloric Acid SCHEMBL3266036 | 0.84 | KDM4E (0.31) | ALDH1A1CYP1A2HPGDCYP2C19KDM4E | |
| Hydrochloric Acid SCHEMBL3266023 | 0.84 | NPC1 (0.34) | RAB9A | |
| Hydrochloric Acid SCHEMBL6156307 | 0.81 | ALDH1A1 (0.33) | ALDH1A1CYP1A2HPGDCYP2C19KDM4E | |
| Hydrochloric Acid SCHEMBL3271300 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL7166920 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL8164839 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL5387181 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1170313-B1 | CROSS-COPOLYMERIZED OLEFIN/STYRENE/DIENE COPOLYMER, PROCESS FOR THE PRODUCTION OF THE SAME AND USES THEREOF | DENKI KAGAKU KOGYO KK (JP) | 2010-06-02 | — | — | EP | disclosed |
| US-7259219-B2 | Low molecular weight copolymer of ethylene and vinyl aromatic monomer and uses thereof | DOW GLOBAL TECHNOLOGIES INC. (US) | 2007-08-21 | — | — | US | disclosed |
| EP-1495059-B1 | LOW MOLECULAR WEIGHT COPOLYMER OF ETHYLENE AND VINYL AROMATIC MONOMER AND USES THEREOF | DOW GLOBAL TECHNOLOGIES INC (US) | 2006-05-24 | — | — | EP | disclosed |
| US-20050165192-A1 | Low molecular weight copolymer of ethylene and vinyl aromatic monomer and uses thereof | DOW GLOBAL TECHNOLOGIES, INC. | 2005-07-28 | — | — | US | disclosed |
| EP-1495059-A1 | LOW MOLECULAR WEIGHT COPOLYMER OF ETHYLENE AND VINYL AROMATIC MONOMER AND USES THEREOF | DOW GLOBAL TECHNOLOGIES INC. (US) | 2005-01-12 | — | — | EP | disclosed |
| US-6790917-B2 | POLYMERIZING A VINYL COMPOUND IN PRESENCE OF A CATALYST OBTAINED BY COMBINING ORGANOTRANSITION METAL COMPOUND, AN ALUMINUM COMPUND OR ALUMOXANE AND A BORON COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-09-14 | — | — | US | disclosed |
| EP-0872492-B1 | Transition metal compound as catalyst component for polymerization, aromatic vinyl compound-olefin copolymer having stereoregularity and method for its preparation by means of the transition metal compound as catalyst component | DENKI KAGAKU KOGYO KK (JP) | 2003-12-03 | — | — | EP | disclosed |
| WO-2003087178-A1 | LOW MOLECULAR WEIGHT COPOLYMER OF ETHYLENE AND VINYL AROMATIC MONOMER AND USES THEREOF | DOW GLOBAL TECHNOLOGIES INC. (US) | 2003-10-23 | — | — | WO | disclosed |
| US-6630215-B1 | Comprised of vinyl aromatic/alpha-olefin random copolymer and plasticizer; substantially no chlorine; flexible, resilient, transparent; radiation resistance; biocompatibility | DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2003-10-07 | — | — | US | disclosed |
| US-6559234-B1 | Firstly provides a novel olefin/styrene/ diene type cross-copolymer having excellent physical properties and mechanical properties, and a novel, efficient and economically excellent process for its production. It provides an efficient | DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2003-05-06 | — | — | US | disclosed |
| US-6489424-B2 | COMPLEX OF ZIRCONIUM, HAFNIUM OR TITANIUM CONTAINING A BENZIDENYL GROUP; STYRENE-OLEFIN COPOLYMER | DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2002-12-03 | — | — | US | disclosed |
| US-6410649-B1 | AROMATIC VINYL COMPOUND-OLEFIN RANDOM COPOLYMER; MOLDING MATERIALS; IMPACT STRENGTH; CHEMICAL RESISTANCE; WATERPROOFING | DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2002-06-25 | — | — | US | disclosed |
| EP-1170313-A1 | CROSS-COPOLYMERIZED OLEFIN/STYRENE/DIENE COPOLYMER, PROCESS FOR THE PRODUCTION OF THE SAME AND USES THEREOF | DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2002-01-09 | — | — | EP | disclosed |
| US-20010051699-A1 | Transition metal catalyst component for polymerization, aromatic vinyl compound polymer having stereoregularity and method for its preparation by means of the catalyst component | DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2001-12-13 | — | — | US | disclosed |
| US-6329479-B1 | POLYMERIZING AROMATIC VINYL COMPOUND AND OLEFIN IN PRESENCE OF POLYMERIZATION CATALYST COMPRISING A TRANSITION METAL COMPOUND AND COCATALYST | DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2001-12-11 | — | — | US | disclosed |
| US-6235855-B1 | METALLOCENE CONTAINING AN UNSUBSTITUTED OR SUBSTITUTED BENZINDENYL GROUP | DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-1069161-A1 | RESIN COMPOSITION | DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2001-01-17 | — | — | EP | disclosed |
| EP-1062957-A1 | MEDICAL MATERIAL AND MEDICAL SUPPLY | DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2000-12-27 | — | — | EP | disclosed |
| EP-0985689-A1 | Aromatic vinyl compound-ethylene copolymer and method for producing the same | DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2000-03-15 | — | — | EP | disclosed |
| EP-0872492-A2 | Transition metal compound as catalyst component for polymerization, aromatic vinyl compound-olefin copolymer having stereoregularity and method for its preparation by means of the transition metal compound as catalyst component | DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1998-10-21 | — | — | EP | disclosed |