SCHEMBL32675249

SCHEMBL32675249

COc1cc(O)c(F)cc1Cl

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.45
MAPT P10636 2/20 0.45
RAB9A P51151 2/20 0.45
GAA P10253 1/20 0.45
TAAR1 Q96RJ0 1/20 0.43
PPOX P50336 1/20 0.42
POLB P06746 1/20 0.42
LMNA P02545 1/20 0.41
TP53 P04637 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
HMGCR P04035 1/20 0.41
KDM4E B2RXH2 2/20 0.41
ALDH1A1 P00352 1/20 0.41
KMT2A Q03164 1/20 0.41
PYGL P06737 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.40
HTT P42858 1/20 0.38
PTGS1 P23219 1/20 0.38
PTGS2 P35354 1/20 0.38
HPGD P15428 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21614370 1.00 NPC1 (0.45) NPC1MAPTRAB9AGAATAAR1
SCHEMBL21611906 0.83 HMGCR (0.41) NPC1MAPTRAB9ALMNAHMGCR
SCHEMBL11392839 0.82 HMGCR (0.52) MAPTRAB9ATAAR1LMNATP53
SCHEMBL24445889 0.80 HMGCR (0.45) MAPTRAB9ATAAR1LMNATP53
SCHEMBL7792597 0.80 NPC1 (0.56) NPC1GAATAAR1HTTHPGD
SCHEMBL23972607 0.79 GAA (0.40) NPC1MAPTRAB9AGAATAAR1
SCHEMBL1098584 0.77 NPC1 (0.47) NPC1MAPTRAB9AGAATAAR1
SCHEMBL19914317 0.77 GAA (0.47) NPC1MAPTRAB9AGAATAAR1
SCHEMBL31457750 0.76 NPC1 (0.42) NPC1MAPTRAB9AGAATAAR1
SCHEMBL6176724 0.76 NPC1 (0.42) NPC1MAPTRAB9AGAATAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4696682-A1 HERBICIDAL THIOCARBAMATES CARRYING AN ETHER-SUBSTITUTED PHENYL RING BASF SE (DE) 2026-02-18 EP disclosed