Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 9/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | RAF1 | P04049 | 1/20 | 0.40 |
| ▸ | BRAF | P15056 | 1/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 3/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | KDR | P35968 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.39 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.39 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.39 |
| ▸ | FLT4 | P35916 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21614370 | 0.83 | NPC1 (0.45) | HMGCRHPGDRAB9AHTTLMNA | |
| SCHEMBL32675249 | 0.83 | NPC1 (0.45) | HMGCRHPGDRAB9AHTTLMNA | |
| SCHEMBL23972607 | 0.83 | GAA (0.40) | HMGCRDPP4RAF1BRAFFLT1 | |
| SCHEMBL19088274 | 0.82 | HTR2A (0.44) | HPGDRAB9AHTTLMNAMAPK1 | |
| SCHEMBL11003488 | 0.82 | HTT (0.48) | HMGCRDPP4HPGDTSHRHSD17B10 | |
| SCHEMBL7792597 | 0.80 | NPC1 (0.56) | DPP4HPGDTSHRHSD17B10KDR | |
| SCHEMBL69147 | 0.80 | HSD17B10 (0.52) | DPP4HPGDTSHRHSD17B10RAB9A | |
| SCHEMBL19756672 | 0.80 | HTR2A (0.47) | HPGDTSHRRAB9AHTTLMNA | |
| SCHEMBL24445889 | 0.80 | HMGCR (0.45) | HMGCRTSHRRAB9AKDRHTT | |
| SCHEMBL17086577 | 0.77 | GLA (0.47) | TSHRRAB9AHTTLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210337789-A1 | Derivatives of m-Guaiacol, Their Preparation and Their Uses | UNIVERSITE DE CAEN NORMANDIE (FR) | 2021-11-04 | — | — | US | disclosed |
| US-20210337789-A1 | Derivatives of m-Guaiacol, Their Preparation and Their Uses | UNIVERSITE DE CAEN NORMANDIE (FR) | 2021-11-04 | — | — | US | disclosed |
| EP-3817551-A1 | M-GUAIACOL DERIVATIVES, PREPARATION THEREOF, AND USES THEREOF | Université de Caen Normandie (FR) | 2021-05-12 | — | — | EP | disclosed |
| WO-2020007882-A1 | M-GUAIACOL DERIVATIVES, PREPARATION THEREOF, AND USES THEREOF | UNIVERSITE DE CAEN NORMANDIE (FR) | 2020-01-09 | — | — | WO | disclosed |
| WO-2020007882-A1 | M-GUAIACOL DERIVATIVES, PREPARATION THEREOF, AND USES THEREOF | UNIVERSITE DE CAEN NORMANDIE (FR) | 2020-01-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210337789-A1 | Derivatives of m-Guaiacol, Their Preparation and Their Uses | MPG, MGLL, GANC | HMGCR 852/4885DPP4 391/4885HPGD 1574/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.