Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | RET | P07949 | 1/20 | 0.42 |
| ▸ | KIF5B | P33176 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | EP300 | Q09472 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24436801 | 0.91 | MAPK1 (0.42) | HMGCRHTTMAPK1LMNARAB9A | |
| SCHEMBL11392839 | 0.88 | HMGCR (0.52) | HMGCRHTTMAPK1LMNARAB9A | |
| SCHEMBL18481797 | 0.82 | LMNA (0.45) | HMGCRHTTMAPK1LMNARAB9A | |
| SCHEMBL16173473 | 0.81 | MAOB (0.46) | HMGCRHTTMAPK1LMNARAB9A | |
| SCHEMBL19914414 | 0.80 | EP300 (0.43) | HMGCRHTTMAPK1LMNARAB9A | |
| SCHEMBL983915 | 0.80 | ALOX5 (0.44) | HMGCRHTTMAPK1LMNARAB9A | |
| SCHEMBL32675249 | 0.80 | NPC1 (0.45) | HMGCRHTTLMNARAB9APTGS2 | |
| SCHEMBL21614370 | 0.80 | NPC1 (0.45) | HMGCRHTTLMNARAB9APTGS2 | |
| SCHEMBL21611906 | 0.80 | HMGCR (0.41) | HMGCRHTTMAPK1LMNARAB9A | |
| SCHEMBL30954137 | 0.80 | EP300 (0.43) | HMGCRHTTMAPK1LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4001336-A1 | POLYURETHANE, POLYURETHANE PRODUCTION METHOD, CONDUCTIVE PASTE COMPOSITION, CONDUCTIVE WIRE, AND METHOD FOR PRODUCING CONDUCTIVE WIRE | Shin-Etsu Chemical Co., Ltd. (JP) | 2022-05-25 | — | — | EP | disclosed |