SCHEMBL3267547

SCHEMBL3267547

C=CCc1cc2ccccc2oc1=O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.54
MAOB P27338 5/20 0.52
MMP2 P08253 1/20 0.51
MMP9 P14780 1/20 0.51
ADAM17 P78536 1/20 0.51
TYR P14679 1/20 0.50
DAO P14920 1/20 0.50
AKR1B1 P15121 1/20 0.50
HPGD P15428 1/20 0.50
POLB P06746 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
SRD5A1 P18405 1/20 0.50
RAB9A P51151 3/20 0.47
KDM4E B2RXH2 2/20 0.47
ALDH1A1 P00352 1/20 0.47
CA12 O43570 3/20 0.46
CA9 Q16790 3/20 0.46
CA1 P00915 2/20 0.46
CA3 P07451 1/20 0.46
TSHR P16473 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8366995 0.85 MAOB (0.57) MAOAMAOBMMP2MMP9ADAM17
SCHEMBL294595 0.81 MAOA (0.58) MAOAMAOBMMP2MMP9ADAM17
SCHEMBL7143401 0.81 MMP2 (0.52) MAOAMAOBMMP2MMP9ADAM17
SCHEMBL7142290 0.81 POLB (0.51) MAOAMAOBMMP2MMP9ADAM17
SCHEMBL9233570 0.81 MAOA (0.51) MAOAMAOBMMP2MMP9ADAM17
SCHEMBL13612673 0.80 MAOA (0.61) MAOAMAOBMMP2MMP9ADAM17
SCHEMBL27625488 0.80 MMP2 (0.67) MAOAMAOBMMP2MMP9ADAM17
SCHEMBL15558092 0.80 VKORC1 (0.54) MAOAMAOBMMP2MMP9ADAM17
SCHEMBL7951064 0.80 SRD5A1 (0.61) AKR1B1HPGDPOLBSRD5A1RAB9A
SCHEMBL1619109 0.79 MAOB (0.67) MAOAMAOBMMP2MMP9ADAM17

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116903570-A Preparation method of 7,3 (2 ', 4') -trihydroxy-5-methoxy-6-isopentenyl coumarin 美迪西普瑞生物医药科技(上海)有限公司 2023-10-20 CN claimed
EP-0698823-B1 Antireflective coating for microlithography IBM (US) 1999-12-29 EP claimed
US-5736301-A USING DEEP ULTRAVIOLET RADIATION INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1998-04-07 US claimed
EP-0698823-A1 Antireflective coating for microlithography International Business Machines Corporation (US) 1996-02-28 EP claimed
US-RE28789-E ETHYLENICALLY UNSATURATED MONOMER; RADIATION ABSORBER E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-04-27 US claimed
CN-116903570-A Preparation method of 7,3 (2 ', 4') -trihydroxy-5-methoxy-6-isopentenyl coumarin 美迪西普瑞生物医药科技(上海)有限公司 2023-10-20 CN disclosed
CN-111808062-B Osthole sulfonate compound and application thereof 遵义医科大学 2022-09-13 CN disclosed
CN-108553417-B Osthole self-emulsifying drug release system and preparation method and application thereof 陕西中医药大学 2022-06-21 CN disclosed
CN-212549078-U Be used for medical science contain osthole's aqueous emulsion stir device 山东第一医科大学(山东省医学科学院) 2021-02-19 CN disclosed
CN-111808062-A Osthole sulfonate compound and application thereof 遵义医科大学 2020-10-23 CN disclosed
CN-108192596-B Coated carboxylated SiO2Preparation method of fluorescent nanosphere 中北大学 2020-07-24 CN disclosed
CN-107163013-B Method for preparing osthole from plant and application of osthole in preparing cosmetics 广州市娇兰化妆品有限公司 2020-04-14 CN disclosed
WO-1999026476-A1 NEW PSORALENS FOR PATHOGEN INACTIVATION CERUS CORPORATION (US) 1999-06-03 WO disclosed
US-5736301-A USING DEEP ULTRAVIOLET RADIATION INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1998-04-07 US disclosed
US-5607824-A UP TO 25 WEIGHT % COPOLYMER OF BISPHENOL A MONOMERS, BENZOPHENONE MONOMERS, AND ANTHRACENE-CONTAINING MONOMERS; AT LEAST 75 WEIGHT % CARRIER FLUID OR SOLVENT INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1997-03-04 US disclosed
EP-0698823-A1 Antireflective coating for microlithography International Business Machines Corporation (US) 1996-02-28 EP disclosed
US-4948694-A CONTAINING PHOTOINITIATOR COMPRISING CAMPHORQUINONE AND COUMARIN DERIVATIVE; SENSITIVITY, STORAGE STABILITY CANON KABUSHIKI KAISHA (JP) 1990-08-14 US disclosed
EP-0133766-A2 Coumarin derivatives, pharmaceutical compositions containing the same, and the use thereof in the treatment of cancer FIDIA S.p.A. (IT) 1985-03-06 EP disclosed
US-4264710-A AN ETHYLENICALLY UNSATURATED COMPOUND, AND A PHOTOPOLYMERIZATION INIATOR FUJI PHOTO FILM CO., LTD. (JP) 1981-04-28 US disclosed
US-RE28789-E ETHYLENICALLY UNSATURATED MONOMER; RADIATION ABSORBER E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-04-27 US disclosed