Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 3/20 | 0.59 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | GLA | P06280 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | CA9 | Q16790 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28164061 | 0.83 | POLB (0.59) | POLBHSD17B3KDM4EMEN1GLA | |
| SCHEMBL30405545 | 0.81 | HSD17B3 (0.65) | POLBHSD17B3KDM4EMEN1GLA | |
| SCHEMBL29066603 | 0.81 | ESR2 (0.61) | POLBHSD17B3KDM4EMEN1GLA | |
| SCHEMBL220708 | 0.81 | HSD17B3 (0.65) | POLBHSD17B3KDM4EMEN1GLA | |
| SCHEMBL16283606 | 0.80 | POLB (0.59) | POLBHSD17B3KDM4EMEN1GLA | |
| SCHEMBL6037595 | 0.80 | POLB (0.59) | POLBHSD17B3KDM4EMEN1GLA | |
| SCHEMBL3267547 | 0.80 | MAOA (0.54) | SRD5A1POLBKDM4EMEN1KMT2A | |
| SCHEMBL2274941 | 0.77 | POLB (0.57) | POLBHSD17B3KDM4EMEN1GLA | |
| SCHEMBL12433441 | 0.77 | POLB (0.57) | POLBHSD17B3KDM4EMEN1GLA | |
| Anemarcoumarin A SCHEMBL774777 | 0.77 | POLB (0.77) | POLBHSD17B3KDM4EMEN1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6255324-B1 | MICROBIOCIDES; SKIN DISORDERS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2001-07-03 | — | — | US | disclosed |