SCHEMBL3267572

SCHEMBL3267572

O=CC1=C(Br)CCc2cc(F)c(F)cc21

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3273769 0.79 PARP1 (0.44)
SCHEMBL3272388 0.79 CYP11B2 (0.42)
SCHEMBL3272250 0.75
SCHEMBL16400955 0.74 SRD5A1 (0.49)
SCHEMBL6618154 0.74 KDM4E (0.45)
SCHEMBL21122868 0.71 PARP10 (0.44)
SCHEMBL3267546 0.71 SRD5A1 (0.46)
SCHEMBL3268773 0.71 F7 (0.44)
SCHEMBL3269854 0.71 MAOA (0.46)
SCHEMBL3268676 0.71 ERN1 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1914229-B1 NOVEL CERCOSPORAMIDE DERIVATIVE DAIICHI SANKYO CO LTD (JP) 2010-06-16 EP disclosed
US-20090036492-A1 Novel Cercosporamide Derivative DAIICHI SANKYO COMPANY, LIMITED (JP) 2009-02-05 US disclosed
EP-1914229-A1 NOVEL CERCOSPORAMIDE DERIVATIVE Daiichi Sankyo Company, Limited (JP) 2008-04-23 EP disclosed