SCHEMBL3267597

SCHEMBL3267597

CCc1ccc2c(F)cc(C)cc2c1C=O

nearest known ligand 0.34

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALB P02768 1/20 0.34
ERN1 O75460 1/20 0.34
ALDH1A1 P00352 1/20 0.34
ALPG P10696 1/20 0.31
SRC P12931 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
CYP19A1 P11511 1/20 0.30
ESR1 P03372 1/20 0.30
ESR2 Q92731 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3267516 0.87 ALB (0.40) ALBERN1ALDH1A1ALPGSRC
SCHEMBL3268869 0.85 CYP19A1 (0.39) ERN1ALDH1A1MEN1KMT2ACYP3A4
SCHEMBL3267174 0.79 CYP3A4 (0.34) ERN1ALDH1A1MEN1KMT2ACYP3A4
SCHEMBL3267610 0.77 GABRA1 (0.39) CYP19A1
SCHEMBL3272295 0.75 ALDH1A1 (0.42) ERN1ALDH1A1MEN1KMT2A
SCHEMBL3273985 0.73 ESR1 (0.40) ERN1ALDH1A1CYP3A4CYP2C9CYP2C19
SCHEMBL289022 0.70 ERN1 (0.41) ERN1ALDH1A1SRCCYP3A4
SCHEMBL3272561 0.70 MEN1 (0.39) ALDH1A1MEN1KMT2ACYP19A1ESR1
SCHEMBL1225897 0.68 ERN1 (0.39) ERN1ALDH1A1SRCMEN1KMT2A
SCHEMBL954498 0.68 CYP3A4 (0.38) ERN1ALDH1A1MEN1KMT2ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1914229-B1 NOVEL CERCOSPORAMIDE DERIVATIVE DAIICHI SANKYO CO LTD (JP) 2010-06-16 EP disclosed
US-20090036492-A1 Novel Cercosporamide Derivative DAIICHI SANKYO COMPANY, LIMITED (JP) 2009-02-05 US disclosed
EP-1914229-A1 NOVEL CERCOSPORAMIDE DERIVATIVE Daiichi Sankyo Company, Limited (JP) 2008-04-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090036492-A1 Novel Cercosporamide Derivative GPR119, CBR3, SLC5A2 ALB 4121/4885ERN1 337/4885ALDH1A1 381/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.