SCHEMBL32676013

SCHEMBL32676013

Cc1noc(C)c1COc1cccc(CCNC(=O)c2ccc3ccccc3n2)c1

nearest known ligand 0.56

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 7/20 0.56
MEN1 O00255 1/20 0.54
KMT2A Q03164 1/20 0.54
MAPT P10636 3/20 0.53
LMNA P02545 3/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
MAPK1 P28482 1/20 0.53
PKM P14618 1/20 0.52
TSHR P16473 1/20 0.52
ATM Q13315 1/20 0.52
NPSR1 Q6W5P4 1/20 0.52
HPGD P15428 3/20 0.52
ALDH1A1 P00352 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32676015 0.92 HPGD (0.62) AKR1C3MEN1KMT2AMAPTLMNA
SCHEMBL32676006 0.84 ALDH1A1 (0.63) MEN1KMT2AMAPTLMNASMN1; SMN2
SCHEMBL30835869 0.84 ALDH1A1 (0.62) MEN1KMT2AMAPTLMNASMN1; SMN2
SCHEMBL30835871 0.77 ALDH1A1 (0.55) MEN1KMT2AMAPTLMNASMN1; SMN2
SCHEMBL32676014 0.76 ALDH1A1 (0.49) MEN1KMT2AMAPTLMNASMN1; SMN2
SCHEMBL32676007 0.75 ALDH1A1 (0.51) MEN1KMT2AMAPTLMNASMN1; SMN2
SCHEMBL32676012 0.75 ALDH1A1 (0.51) MEN1KMT2AMAPTLMNASMN1; SMN2
SCHEMBL32676017 0.74 LMNA (0.50) MEN1KMT2AMAPTLMNASMN1; SMN2
SCHEMBL32676009 0.74 ALDH1A1 (0.70) MEN1KMT2AMAPTLMNASMN1; SMN2
SCHEMBL30835951 0.74 MAPT (0.49) MEN1KMT2AMAPTLMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260049064-A1 PROTEIN:PROTEIN INTERACTION INHIBITORS PURDUE RESEARCH FOUNDATION (US) 2026-02-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260049064-A1 PROTEIN:PROTEIN INTERACTION INHIBITORS PRMT6, PRMT5, PRMT1 AKR1C3 4260/4885MEN1 3416/4885KMT2A 828/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.