Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | PDE5A | O76074 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32677128 | 1.00 | KDM4E (0.52) | KDM4EHSD17B10CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL32677140 | 1.00 | KDM4E (0.52) | KDM4EHSD17B10CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL32677091 | 0.84 | KDM4E (0.53) | KDM4EHSD17B10CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL32676819 | 0.84 | KDM4E (0.53) | KDM4EHSD17B10CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL32677208 | 0.84 | KDM4E (0.53) | KDM4EHSD17B10CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL3429946 | 0.84 | KDM4E (0.53) | KDM4EHSD17B10CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL1869613 | 0.83 | KDM4E (0.52) | KDM4EHSD17B10CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL32676935 | 0.83 | KDM4E (0.52) | KDM4EHSD17B10CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL16271252 | 0.83 | KDM4E (0.52) | KDM4EHSD17B10CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL31651844 | 0.83 | KDM4E (0.52) | KDM4EHSD17B10CYP1A2CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260049060-A1 | TETRAHYDROISOQUINOLINYLMETHYLBENZAMIDE COMPOUNDS | NATIONAL HEALTH RES INST (TW) | 2026-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260049060-A1 | TETRAHYDROISOQUINOLINYLMETHYLBENZAMIDE COMPOUNDS | OPRK1, OPRD1, OPRM1 | KDM4E 4158/4885HSD17B10 879/4885CYP1A2 482/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.