SCHEMBL32677484

SCHEMBL32677484

O=C(O)[C@H]1CCCN1C(=O)COc1ccc(C(F)(F)F)cc1

nearest known ligand 0.52

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.52
L3MBTL1 Q9Y468 1/20 0.50
KMT2A Q03164 2/20 0.49
ENPP2 Q13822 3/20 0.48
DGAT1 O75907 1/20 0.48
CPT2 P23786 4/20 0.47
CPT1A P50416 4/20 0.47
NPSR1 Q6W5P4 1/20 0.47
DPP4 P27487 1/20 0.47
HRH3 Q9Y5N1 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3187180 0.90 ALDH1A1 (0.61) ALDH1A1L3MBTL1KMT2ACPT2CPT1A
SCHEMBL3187156 0.90 ALDH1A1 (0.61) ALDH1A1L3MBTL1KMT2ACPT2CPT1A
SCHEMBL31710554 0.89 DPP4 (0.59) ALDH1A1KMT2AENPP2CPT2CPT1A
SCHEMBL5741958 0.86 KMT2A (0.65) ALDH1A1L3MBTL1KMT2ACPT2CPT1A
SCHEMBL5741952 0.86 KMT2A (0.65) ALDH1A1L3MBTL1KMT2ACPT2CPT1A
SCHEMBL5743864 0.84 ALDH1A1 (0.63) ALDH1A1L3MBTL1KMT2ACPT2CPT1A
SCHEMBL3148212 0.84 ALDH1A1 (0.63) ALDH1A1L3MBTL1KMT2ACPT2CPT1A
SCHEMBL5743406 0.84 L3MBTL1 (0.60) ALDH1A1L3MBTL1KMT2ACPT2CPT1A
SCHEMBL5743409 0.84 L3MBTL1 (0.60) ALDH1A1L3MBTL1KMT2ACPT2CPT1A
SCHEMBL5741156 0.84 ALDH1A1 (0.58) ALDH1A1L3MBTL1KMT2ADGAT1CPT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260055057-A1 GLUCOSE-DEPENDENT INSULINOTROPIC POLYPEPTIDE RECEPTOR ANTAGONISTS AND USES THEREOF PFIZER INC. (US) 2026-02-26 US disclosed
WO-2026042018-A1 4-{4-[(1-{[4-(PROPAN-2-YL)PHENYL]CARBAMOYL)-D-PROLYL)AMINO]CYCLOHEXYL}BENZOIC ACID DERIVATIVES AS GIPR ANTAGONISTS FOR THE TREATMENT OF DIABETES PFIZER INC. (US) 2026-02-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260055057-A1 GLUCOSE-DEPENDENT INSULINOTROPIC POLYPEPTIDE RECEPTOR ANTAGONISTS AND USES THEREOF GIPR, GLP1R, GPR119 ALDH1A1 2197/4885L3MBTL1 1022/4885KMT2A 3714/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.