Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 5/20 | 0.40 |
| ▸ | TNF | P01375 | 4/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.37 |
| ▸ | MPO | P05164 | 3/20 | 0.36 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.35 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.35 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32677656 | 1.00 | RIPK1 (0.40) | RIPK1TNFGPR84HTR2AGPR17 | |
| SCHEMBL24420520 | 0.82 | GPR84 (0.44) | RIPK1TNFGPR84HTR2ASLC6A4 | |
| SCHEMBL2536517 | 0.80 | HTR2A (0.62) | HTR2ASLC6A4MPO | |
| SCHEMBL32677601 | 0.79 | GPR84 (0.39) | RIPK1TNFGPR84HTR2AGPR17 | |
| SCHEMBL32677596 | 0.79 | GPR84 (0.39) | RIPK1TNFGPR84HTR2AGPR17 | |
| Hydrochloric Acid SCHEMBL21546026 | 0.79 | HTR2A (0.60) | HTR2ASLC6A4MPO | |
| SCHEMBL13715436 | 0.75 | HTR2A (0.65) | RIPK1TNFGPR84HTR2ASLC6A4 | |
| SCHEMBL26912665 | 0.73 | GPR17 (0.34) | GPR17CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL20355043 | 0.73 | GPR17 (0.34) | GPR17CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL29951655 | 0.72 | TRIM24 (0.47) | GPR17ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026041636-A1 | MACROCYCLE COMPOUNDS FOR THE TREATMENT OF CANCER | F. HOFFMANN-LA ROCHE AG (CH) | 2026-02-26 | — | — | WO | disclosed |