Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.39 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.38 |
| ▸ | MPO | P05164 | 6/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | TNF | P01375 | 3/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32677596 | 1.00 | GPR84 (0.39) | GPR84GPR17MPOSLC6A4TNF | |
| SCHEMBL24420520 | 0.82 | GPR84 (0.44) | GPR84MPOSLC6A4TNFRIPK1 | |
| SCHEMBL32677653 | 0.79 | RIPK1 (0.40) | GPR84GPR17MPOSLC6A4TNF | |
| SCHEMBL32677656 | 0.79 | RIPK1 (0.40) | GPR84GPR17MPOSLC6A4TNF | |
| SCHEMBL31188783 | 0.75 | DYRK1A (0.50) | GPR84MPOSLC6A4PIM1PIM3 | |
| SCHEMBL13715520 | 0.75 | DYRK1A (0.50) | GPR84MPOSLC6A4PIM1PIM3 | |
| SCHEMBL32677627 | 0.73 | BRPF1 (0.51) | GPR17TNFPIM1PIM3ALDH1A1 | |
| SCHEMBL22789976 | 0.72 | GPR17 (0.47) | GPR17PIM1PIM3ALDH1A1 | |
| SCHEMBL21624174 | 0.72 | GPR84 (0.50) | GPR84MPOSLC6A4HTR2A | |
| SCHEMBL29956475 | 0.72 | PIM3 (0.55) | GPR17PIM1PIM3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026041636-A1 | MACROCYCLE COMPOUNDS FOR THE TREATMENT OF CANCER | F. HOFFMANN-LA ROCHE AG (CH) | 2026-02-26 | — | — | WO | disclosed |