Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP46A1 | Q9Y6A2 | 5/20 | 0.38 |
| ▸ | PRKCA | P17252 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.38 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32678012 | 1.00 | F10 (0.49) | F10KDM4EALDH1A1GLAGAA | |
| SCHEMBL32678004 | 0.82 | F10 (0.54) | F10KDM4EALDH1A1GLAGAA | |
| SCHEMBL20604844 | 0.79 | PIM1 (0.48) | F10KDM4EALDH1A1GLAGAA | |
| SCHEMBL394319 | 0.79 | KDM4E (0.47) | F10KDM4EALDH1A1GLAGAA | |
| SCHEMBL19943318 | 0.77 | MAPT (0.49) | KDM4EGAAMAPTCYP46A1PIM2 | |
| SCHEMBL7134019 | 0.75 | OPRK1 (0.58) | KDM4EMAPTLMNAL3MBTL1OPRK1 | |
| SCHEMBL28697754 | 0.72 | MAPT (0.43) | F10KDM4EALDH1A1GLAGAA | |
| SCHEMBL9883424 | 0.71 | OGA (0.46) | KDM4EALDH1A1MAPTNPC1HPGD | |
| SCHEMBL31752976 | 0.71 | HRH3 (0.57) | KDM4EALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL7134528 | 0.70 | ALDH1A1 (0.58) | KDM4EALDH1A1MAPTNPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260055108-A1 | TRIAZINE COMPOUNDS AND USES THEREOF | HUTCHMED LTD (CN) | 2026-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260055108-A1 | TRIAZINE COMPOUNDS AND USES THEREOF | CBR1, CNR1, CBR3 | F10 4227/4885KDM4E 3502/4885ALDH1A1 1308/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.