Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5574276 | 1.00 | TSHR (0.47) | TSHRLMNACYP2A6PDK2CYP1A2 | |
| SCHEMBL9299768 | 1.00 | TSHR (0.47) | TSHRLMNACYP2A6PDK2CYP1A2 | |
| Iodide SCHEMBL28991660 | 0.97 | TSHR (0.45) | TSHRLMNACYP2A6PDK2CYP1A2 | |
| Hydrochloric Acid SCHEMBL29020357 | 0.97 | TSHR (0.45) | TSHRLMNACYP2A6PDK2CYP1A2 | |
| SCHEMBL7912309 | 0.80 | PTPRC (0.59) | LMNANPC1RAB9ASMN1; SMN2ADORA2A | |
| SCHEMBL8668864 | 0.80 | MEN1 (0.55) | TSHRLMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8671883 | 0.80 | ADORA2A (0.57) | LMNACYP1A2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2469822 | 0.80 | CYP2A6 (0.55) | TSHRLMNACYP2A6PDK2CYP1A2 | |
| SCHEMBL29236876 | 0.78 | ALDH1A1 (0.47) | TSHRLMNACYP1A2NPC1RAB9A | |
| SCHEMBL1696361 | 0.77 | CYP2A6 (0.65) | TSHRLMNACYP2A6PDK2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2031967-B1 | USE OF MICROBIOLOGICAL CONSORTIA OF RHIZOSPHERE FOR POLLUTANTS ELIMINATION AND NITRATES REDUCTION IN AGRICULTURAL PRODUCTS | CCS AOSTA S R L (IT) | 2010-03-10 | — | — | EP | claimed |
| EP-0979809-B1 | Process for the preparation of 4-chlorobiphenylenes | CLARIANT GMBH (DE) | 2003-01-29 | — | — | EP | claimed |
| EP-0979809-A1 | Process for the preparation of 4-chlorobiphenylenes | Clariant GmbH (DE) | 2000-02-16 | — | — | EP | claimed |
| EP-0503831-B1 | Destruction of polychlorinated biphenyls | ONTARIO HYDRO (CA) | 1997-09-17 | — | — | EP | claimed |
| EP-0625967-A1 | N,N'-SUBSTITUTED IMIDOCARBONIMIDIC DIAMIDES DERIVED FROM HYDROXYLAMINES. | JACOBUS PHARMA CO INC (US) | 1994-11-30 | — | — | EP | claimed |
| WO-1993016037-A1 | N,N'-SUBSTITUTED IMIDOCARBONIMIDIC DIAMIDES DERIVED FROM HYDROXYLAMINES | JACOBUS PHARMACEUTICAL CO., INC. (US) | 1993-08-19 | — | — | WO | claimed |
| US-4794871-A | Method and installation for the treatment of material contaminated with toxic organic compounds | ENVIRONMENT PROTECTION ENGINEERS, INC. (US) | 1989-01-03 | — | — | US | claimed |
| EP-0257260-A1 | Process for the hydrogenation treatment of mineral oils contaminated by chlorobiphenyls | VEBA OEL Technologie und Automatisierung GmbH (DE) | 1988-03-02 | — | — | EP | claimed |
| CN-102365133-B | Compositions for multilayer coating and resins therefore | SHERWIN WILLIAMS CO | 2014-01-29 | — | — | CN | disclosed |
| CN-101815758-B | Amine functional adducts and curable compositions comprising the same | SHERWIN WILLIAMS CO | 2013-07-31 | — | — | CN | disclosed |
| CN-102365133-A | Compositions for multilayer coating and resins therefore | SHERWIN WILLIAMS CO | 2012-02-29 | — | — | CN | disclosed |
| CN-101980796-A | Ambient cure painting method | SHERWIN WILLIAMS CO | 2011-02-23 | — | — | CN | disclosed |
| CN-101910230-A | Epoxy resin composition containing isocyanurates for use in electrical laminates | DOW GLOBAL TECHNOLOGIES INC | 2010-12-08 | — | — | CN | disclosed |
| CN-101815758-A | Amine functional adducts and curable compositions comprising the same | SHERWIN WILLIAMS CO | 2010-08-25 | — | — | CN | disclosed |
| EP-0170808-A1 | Process for removing polychlorinated biphenyl (PCB) from electrically insulating fluids | DIDIER-WERKE AG (DE) | 1986-02-12 | — | — | EP | disclosed |
| US-4507465-A | IMPACT STRENGTH | TORAY INDUSTRIES, INC. (JP) | 1985-03-26 | — | — | US | disclosed |
| EP-0113252-A2 | Process for producing block copolyamide | TORAY INDUSTRIES, INC. (JP) | 1984-07-11 | — | — | EP | disclosed |
| EP-0070789-A2 | Method of destroying compounds based on organic materials containing sulphur and/or halogens and/or toxic metals, and applications of said method | CIRTA Centre International de Recherches et de Technologies Appliquées (FR) | 1983-01-26 | — | — | EP | disclosed |
| EP-0008251-B1 | DIELECTRIC LIQUIDS, MANUFACTURING PROCESS AND USES | P C U K PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1982-02-17 | — | — | EP | disclosed |
| EP-0008251-A1 | Dielectric liquids, manufacturing process and uses | P C U K PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1980-02-20 | — | — | EP | disclosed |