SCHEMBL2469822

SCHEMBL2469822

Clc1ccccc1-c1c(Cl)cccc1Cl

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 3/20 0.55
LMNA P02545 2/20 0.50
TSHR P16473 2/20 0.50
NPC1 O15118 2/20 0.46
RAB9A P51151 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
TP53 P04637 1/20 0.46
HPGD P15428 1/20 0.46
DPP4 P27487 1/20 0.44
PDK2 Q15119 1/20 0.44
CYP1A2 P05177 2/20 0.43
ALDH1A1 P00352 2/20 0.43
HSD11B1 P28845 1/20 0.43
IDO1 P14902 1/20 0.41
ADORA2A P29274 1/20 0.40
NOTUM Q6P988 1/20 0.40
MAPK14 Q16539 1/20 0.40
PTPRC P08575 1/20 0.40
LDHA P00338 1/20 0.40
POLB P06746 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29387186 0.83 CYP2A6 (0.50) CYP2A6LMNATSHRNPC1RAB9A
SCHEMBL4450486 0.83 CYP2A6 (0.50) CYP2A6LMNATSHRNPC1RAB9A
SCHEMBL4621457 0.83 ALDH1A1 (0.54) CYP2A6LMNATSHRNPC1RAB9A
SCHEMBL30562809 0.83 TSHR (0.54) CYP2A6LMNATSHRNPC1RAB9A
SCHEMBL521542 0.83 PLA2G7 (0.50) CYP2A6LMNATSHRNPC1RAB9A
SCHEMBL23609502 0.83 HSD11B1 (0.46) CYP2A6LMNATSHRNPC1RAB9A
SCHEMBL4459058 0.81 CYP2A6 (0.48) CYP2A6LMNATSHRNPC1RAB9A
SCHEMBL30378025 0.81 CYP2A6 (0.48) CYP2A6LMNATSHRNPC1RAB9A
SCHEMBL29883244 0.81 CYP2A6 (0.67) CYP2A6LMNATSHRNPC1RAB9A
SCHEMBL29802156 0.81 CYP2A6 (0.67) CYP2A6LMNATSHRNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP claimed
CN-115938408-B Disk device 株式会社东芝 2025-06-03 CN disclosed
CN-119785837-A Disk device 株式会社东芝 2025-04-08 CN disclosed
CN-112405632-B Hand-held personal care device with light system 皇家飞利浦有限公司 2025-03-14 CN disclosed
CN-114267383-B Disk device 株式会社 东芝 2025-01-21 CN disclosed
CN-114203206-B Disk device 株式会社 东芝 2025-01-03 CN disclosed
CN-118893908-A Domestic frivolous dull and stereotyped pyrograph machine of type intelligence 义乌尚美特科技有限公司 2024-11-05 CN disclosed
CN-115066806-B Dielectric ceramic filter 株式会社KMW 2024-10-22 CN disclosed
CN-116710828-B Method and optical microscope having multiple photon counting detector element arrays 卡尔蔡司显微镜有限责任公司 2024-09-27 CN disclosed
CN-118681348-A Active obstacle-avoidance high-efficiency dust remover and method suitable for open space 西南科技大学 2024-09-24 CN disclosed
CN-106770697-B Method for determining chlorobenzene compounds in plastic products 东莞出入境检验检疫局检验检疫综合技术中心 2019-05-10 CN disclosed
US-20160279456-A1 POLYCHLORINATED BIPHENYL DETOXIFYING COMPLEX COMPOSITION AND METHOD FOR MANUFACTURING SAME NATIONAL UNIVERSITY CORPORATION YAMAGATA UNIVERSITY (JP) 2016-09-29 US disclosed
EP-1635914-B1 METHOD FOR DEHALOGENATION DETOXICATION OF HALOGENATED AROMATIC AND/OR CYCLIC COMPOUNDS ZDRAVOTNI USTAV SE SIDLEM V OSTRAVE (CZ) 2011-10-05 EP disclosed
US-7767873-B2 Method for dehalogenation detoxication of halogenated aromatic and/or cyclic compounds ZDRAVOTNI USTAV SE SIDLEM V OSTRAVE (CZ) 2010-08-03 US disclosed
US-20090269857-A1 Instruments for detecting low-molecular weight substance FUJIKURA KASEI CO., LTD. (JP) 2009-10-29 US disclosed
US-20070021639-A1 Method for dehalogenation detoxication of halogenated aromatic and/or cyclic compounds ZDRAVOTNI USTAV SE SIDLEM V OSTRAVE (CZ) 2007-01-25 US disclosed
EP-1635914-A1 METHOD FOR DEHALOGENATION DETOXICATION OF HALOGENATED AROMATIC AND/OR CYCLIC COMPOUNDS Ustav Chemickych Procesu Akademie Ved Ceské Republiky (CZ) 2006-03-22 EP disclosed
US-20050148097-A1 Instruments for detecting low-molecular weight substance ENBIOTEC LABORATORIES C., LTD. (JP) 2005-07-07 US disclosed
EP-1489420-A1 INSTRUMENTS FOR DETECTING LOW-MOLECULAR WEIGHT SUBSTANCE Enbiotec Laboratories Co., Ltd. (JP) 2004-12-22 EP disclosed
WO-2004096371-A1 METHOD FOR DEHALOGENATION DETOXICATION OF HALOGENATED AROMATIC AND/OR CYCLIC COMPOUNDS USTAV CHEMICKYCH PROCESU AV CR (CZ) 2004-11-11 WO disclosed