Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3267863 | 1.00 | TSHR (0.47) | TSHRLMNACYP2A6PDK2CYP1A2 | |
| SCHEMBL9299768 | 1.00 | TSHR (0.47) | TSHRLMNACYP2A6PDK2CYP1A2 | |
| Iodide SCHEMBL28991660 | 0.97 | TSHR (0.45) | TSHRLMNACYP2A6PDK2CYP1A2 | |
| Hydrochloric Acid SCHEMBL29020357 | 0.97 | TSHR (0.45) | TSHRLMNACYP2A6PDK2CYP1A2 | |
| SCHEMBL7912309 | 0.80 | PTPRC (0.59) | LMNANPC1RAB9ASMN1; SMN2ADORA2A | |
| SCHEMBL8668864 | 0.80 | MEN1 (0.55) | TSHRLMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8671883 | 0.80 | ADORA2A (0.57) | LMNACYP1A2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2469822 | 0.80 | CYP2A6 (0.55) | TSHRLMNACYP2A6PDK2CYP1A2 | |
| SCHEMBL29236876 | 0.78 | ALDH1A1 (0.47) | TSHRLMNACYP1A2NPC1RAB9A | |
| SCHEMBL1696361 | 0.77 | CYP2A6 (0.65) | TSHRLMNACYP2A6PDK2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1835007-A2 | Nanofibres from functionalised organic molecules | Carl von Ossietzky Universität Oldenburg (DE) | 2007-09-19 | — | — | EP | disclosed |