SCHEMBL3267974

SCHEMBL3267974

O=C(Cl)OCc1c(F)c(F)c(F)c(F)c1COC(=O)Cl

nearest known ligand 0.43

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.43
MMP1 P03956 1/20 0.39
MMP2 P08253 1/20 0.39
MMP9 P14780 1/20 0.39
MMP12 P39900 1/20 0.39
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
TDP1 Q9NUW8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5017690 0.95 ALDH1A1 (0.43) ALDH1A1MMP1MMP2MMP9MMP12
SCHEMBL3691321 0.75 MMP1 (0.44) ALDH1A1MMP1MMP2MMP9MMP12
SCHEMBL22917350 0.74 MMP1 (0.53) ALDH1A1MMP1MMP2MMP9MMP12
SCHEMBL11867729 0.71 NQO1 (0.46) ALDH1A1MMP1MMP2MMP9MMP12
SCHEMBL44341 0.71 CA2 (0.46) ALDH1A1MMP1MMP2MMP9MMP12
SCHEMBL3843282 0.71 TSHR (0.43) ALDH1A1MMP1MMP2MMP9MMP12
SCHEMBL3691322 0.70 MMP1 (0.41) ALDH1A1MMP1MMP2MMP9MMP12
SCHEMBL13811654 0.68 MMP1 (0.40) ALDH1A1MMP1MMP2MMP9MMP12
SCHEMBL14462589 0.68 MMP1 (0.40) ALDH1A1MMP1MMP2MMP9MMP12
SCHEMBL17634992 0.68 MEN1 (0.42) ALDH1A1MMP1MMP2MMP9MMP12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1458792-B1 FLUORINATED POLYIMIDES SHOWA DENKO KK (JP) 2010-06-16 EP disclosed
US-7112647-B2 Fluorinated polymer SHOWA DENKO K.K. (JP) 2006-09-26 US disclosed
US-20050080230-A1 good heat resistance, excellent water repellency, excellent optical characteristics, and particularly superior transparency in a wavelength range from visible to near infrared SHOWA DENKO K.K. (JP) 2005-04-14 US disclosed