Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 2/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 10/20 | 0.42 |
| ▸ | FCER2 | P06734 | 1/20 | 0.41 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3268315 | 0.88 | GHSR (0.45) | GHSRMMP9MMP8TACR1F2 | |
| SCHEMBL3274946 | 0.86 | MMP9 (0.45) | GHSRMMP9MMP8TACR1FCER2 | |
| SCHEMBL3274925 | 0.85 | MMP9 (0.45) | GHSRMMP9MMP8TACR1FCER2 | |
| SCHEMBL6320694 | 0.85 | MMP9 (0.56) | GHSRMMP9MMP8FCER2F2 | |
| SCHEMBL8235025 | 0.84 | GHSR (0.49) | GHSRMMP9MMP8FCER2F2 | |
| SCHEMBL3266844 | 0.83 | GHSR (0.48) | GHSRMMP9MMP8FCER2CAPN1 | |
| SCHEMBL6846643 | 0.83 | GHSR (0.42) | GHSRTACR1 | |
| SCHEMBL3266848 | 0.83 | GHSR (0.42) | GHSRTACR1 | |
| SCHEMBL3272667 | 0.82 | MMP9 (0.44) | MMP9MMP8 | |
| SCHEMBL27533371 | 0.82 | MMP9 (0.44) | MMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1506969-B1 | Compounds with growth hormone releasing properties | HELSINN THERAPEUTICS US INC (US) | 2010-06-09 | — | — | EP | claimed |
| EP-1506969-B1 | Compounds with growth hormone releasing properties | HELSINN THERAPEUTICS US INC (US) | 2010-06-09 | — | — | EP | disclosed |
| EP-1506969-A1 | Compounds with growth hormone releasing properties | NOVO NORDISK A/S (DK) | 2005-02-16 | — | — | EP | disclosed |
| EP-1047709-B1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK AS (DK) | 2004-11-03 | — | — | EP | disclosed |
| EP-1047709-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 2000-11-02 | — | — | EP | disclosed |
| WO-1999036431-A9 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK AS (DK) | 2000-07-27 | — | — | WO | disclosed |
| US-6083908-A | TREATING MEDICAL DISORDERS RESULTING FROM DEFICIENCY IN GROWTH HORMONE | NOVO NORDISK A/S (DK) | 2000-07-04 | — | — | US | disclosed |
| WO-1999036431-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1999-07-22 | — | — | WO | disclosed |