Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | CSF1R | P07333 | 1/20 | 0.42 |
| ▸ | RET | P07949 | 1/20 | 0.42 |
| ▸ | IGF1R | P08069 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL685036 | 1.00 | TDP1 (0.44) | TDP1MAPTALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL686110 | 0.90 | MAPT (0.44) | MAPTALDH1A1CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL27031322 | 0.87 | ALDH1A1 (0.56) | TDP1MAPTALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL16955129 | 0.87 | TDP1 (0.58) | TDP1MAPTALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL14321618 | 0.83 | TRPA1 (0.57) | TDP1MAPTALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL4145981 | 0.80 | TDP1 (0.49) | TDP1MAPTALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL4304248 | 0.79 | MAPT (0.51) | TDP1MAPTALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL9125892 | 0.79 | HTT (0.53) | TDP1MAPTALDH1A1HSP90AA1HPGD | |
| SCHEMBL686111 | 0.78 | MAPT (0.44) | MAPTALDH1A1CYP2C9CYP2C19HPGD | |
| SCHEMBL30263061 | 0.78 | PTGS2 (0.49) | MAPTALDH1A1HPGDSMN1; SMN2TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260069602-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS | ACONCAGUA BIO INC (US) | 2026-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260069602-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS | SCTR, SSTR1, NPY1R | TDP1 1946/4885MAPT 3266/4885ALDH1A1 2807/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.