SCHEMBL32684017

SCHEMBL32684017

Cc1[nH]c2c(Cl)cccc2c1C[C@H](N)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.47
MEN1 O00255 4/20 0.47
KMT2A Q03164 4/20 0.47
KDM4E B2RXH2 3/20 0.47
GAA P10253 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.45
HPGD P15428 1/20 0.44
GRIK1 P39086 2/20 0.42
GRIA1 P42261 2/20 0.42
GRIA2 P42262 2/20 0.42
GRIA3 P42263 2/20 0.42
GRIA4 P48058 2/20 0.42
GRIK5 Q16478 2/20 0.42
TSHR P16473 2/20 0.42
ALDH1A1 P00352 2/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
GRIK2 Q13002 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18029308 1.00 MAPT (0.47) MAPTMEN1KMT2AKDM4EGAA
SCHEMBL19871249 0.86 MAPT (0.63) MAPTMEN1KMT2AKDM4EGAA
SCHEMBL18029059 0.85 MAPT (0.48) MAPTMEN1KMT2AKDM4EGAA
SCHEMBL19871258 0.85 KDM4E (0.48) MAPTMEN1KMT2AKDM4EGAA
SCHEMBL18029279 0.84 MAPT (0.47) MAPTMEN1KMT2AKDM4EGAA
SCHEMBL32684014 0.84 OPRM1 (0.52) MAPTMEN1KMT2AKDM4EGAA
SCHEMBL19871254 0.84 OPRM1 (0.52) MAPTMEN1KMT2AKDM4EGAA
SCHEMBL18029097 0.84 MAPT (0.44) MAPTMEN1KMT2AKDM4EGAA
SCHEMBL18029374 0.82 MAPT (0.45) MAPTMEN1KMT2AKDM4EGAA
SCHEMBL18509914 0.82 MAPT (0.45) MAPTMEN1KMT2AKDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260071243-A1 BIOLOGICAL PRODUCTION OF TRYPTOPHAN-DERIVED PRODUCTS UNIV TEXAS (US) 2026-03-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260071243-A1 BIOLOGICAL PRODUCTION OF TRYPTOPHAN-DERIVED PRODUCTS TPH1, TPH2, SLC6A4 MAPT 1647/4885MEN1 3917/4885KMT2A 1283/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.