Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 5/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 6/20 | 0.39 |
| ▸ | LPL | P06858 | 2/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.38 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23761312 | 0.83 | PIK3CG (0.45) | PIK3CGPIK3CD | |
| SCHEMBL963746 | 0.78 | HTR2A (0.41) | PIK3CGPIK3CDTLR8LPLLIPG | |
| SCHEMBL20641321 | 0.67 | PIK3CG (0.44) | PIK3CGPIK3CD | |
| SCHEMBL20641333 | 0.67 | PIK3CG (0.44) | PIK3CGPIK3CD | |
| SCHEMBL744191 | 0.67 | HSD11B1 (0.37) | LPLLIPGHTR2A | |
| Bromide SCHEMBL23356680 | 0.66 | PIK3CG (0.43) | PIK3CGPIK3CD | |
| SCHEMBL21835232 | 0.66 | KDM4E (0.39) | — | |
| SCHEMBL3637622 | 0.66 | NUDT1 (0.45) | TLR8 | |
| SCHEMBL23761284 | 0.65 | PIK3CG (0.43) | PIK3CGPIK3CD | |
| SCHEMBL31264190 | 0.65 | PIK3CG (0.45) | PIK3CGPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010007100-A1 | 7-SUBSTITUTED AMINO TRIAZOLES AS PI3K INHIBITORS | CELLZOME LTD (GB) | 2010-01-21 | — | — | WO | disclosed |