Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 3/20 | 0.32 |
| ▸ | PIM2 | Q9P1W9 | 3/20 | 0.32 |
| ▸ | KDR | P35968 | 3/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.31 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27086116 | 0.81 | PARP1 (0.43) | GRM2KDRPARP1HTTNCOA1 | |
| SCHEMBL32686609 | 0.81 | PIK3CD (0.38) | GRM2KDRPARP1PIK3CDPIK3CB | |
| SCHEMBL32686554 | 0.78 | PIM1 (0.38) | GRM2PIM1PARP1PIK3CDPIK3CB | |
| SCHEMBL29841781 | 0.78 | HTR2A (0.38) | GRM2PIM1KDRPARP1PIK3CD | |
| SCHEMBL21200175 | 0.78 | HTR2A (0.38) | GRM2PIM1KDRPARP1PIK3CD | |
| SCHEMBL27085852 | 0.77 | GRM2 (0.44) | GRM2PIM1KDRPIK3CDPIK3CB | |
| SCHEMBL32686456 | 0.76 | CBLB (0.36) | KDR | |
| SCHEMBL32686271 | 0.76 | GRM2 (0.33) | GRM2PIM1PIM2SCN9A | |
| SCHEMBL32686624 | 0.73 | CLK1 (0.38) | GRM2PIM1KDRPIK3CDPIK3CB | |
| SCHEMBL27085865 | 0.73 | PIM1 (0.49) | GRM2PIM1KDRPIK3CDPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709718-A1 | 6-SUBSTITUTED-3-PHENYL-ISOINDOLIN-1-ONES AS CBL-B INHIBITORS SELECTIVE OVER C-CBL | Genentech Inc. (US) | 2026-03-18 | — | — | EP | disclosed |