Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 2/20 | 0.33 |
| ▸ | PIM1 | P11309 | 4/20 | 0.31 |
| ▸ | PIM2 | Q9P1W9 | 3/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.30 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.30 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.30 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29920437 | 0.81 | ALDH1A1 (0.42) | PIM1PIM2 | |
| SCHEMBL27085830 | 0.81 | ALDH1A1 (0.42) | PIM1PIM2 | |
| SCHEMBL32686205 | 0.80 | DRD1 (0.38) | GRM2PIM1CSNK1A1CDK5ROCK1 | |
| SCHEMBL32686554 | 0.79 | PIM1 (0.38) | GRM2SCN9APIM1CSNK1A1CDK5 | |
| SCHEMBL30598890 | 0.78 | GRM2 (0.35) | GRM2PIM1CSNK1A1CDK5ROCK1 | |
| SCHEMBL21200740 | 0.78 | GRM2 (0.35) | GRM2PIM1CSNK1A1CDK5ROCK1 | |
| SCHEMBL30004086 | 0.77 | GRM2 (0.42) | GRM2PIM1CSNK1A1CDK5ROCK1 | |
| SCHEMBL27086356 | 0.77 | GRM2 (0.42) | GRM2PIM1CSNK1A1CDK5ROCK1 | |
| SCHEMBL32686292 | 0.76 | GRM2 (0.35) | GRM2SCN9APIM1PIM2 | |
| SCHEMBL25415363 | 0.72 | CDK5 (0.50) | GRM2PIM1CSNK1A1CDK5ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709718-A1 | 6-SUBSTITUTED-3-PHENYL-ISOINDOLIN-1-ONES AS CBL-B INHIBITORS SELECTIVE OVER C-CBL | Genentech Inc. (US) | 2026-03-18 | — | — | EP | disclosed |