Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 8/20 | 0.34 |
| ▸ | PIM1 | P11309 | 3/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.32 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.32 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.32 |
| ▸ | CSF1R | P07333 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.31 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.31 |
| ▸ | LCK | P06239 | 2/20 | 0.31 |
| ▸ | RET | P07949 | 2/20 | 0.31 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.31 |
| ▸ | BLK | P51451 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27085852 | 0.78 | GRM2 (0.44) | GRM2KDRPIM1ROCK1CLK4 | |
| SCHEMBL27085865 | 0.76 | PIM1 (0.49) | GRM2KDRPIM1ROCK1CLK4 | |
| SCHEMBL32686624 | 0.76 | CLK1 (0.38) | GRM2KDRPIM1ROCK1CLK4 | |
| SCHEMBL32686419 | 0.76 | CDK5 (0.41) | GRM2KDRPIM1ROCK1CLK4 | |
| SCHEMBL27086116 | 0.76 | PARP1 (0.43) | GRM2KDRMAPTKDM4E | |
| SCHEMBL29841781 | 0.73 | HTR2A (0.38) | GRM2KDRPIM1ROCK1CLK4 | |
| SCHEMBL29841679 | 0.73 | GRM2 (0.40) | GRM2KDRPIM1ROCK1CLK4 | |
| SCHEMBL21200175 | 0.73 | HTR2A (0.38) | GRM2KDRPIM1ROCK1CLK4 | |
| SCHEMBL29089792 | 0.73 | GRM2 (0.40) | GRM2KDRPIM1ROCK1CLK4 | |
| SCHEMBL32686609 | 0.72 | PIK3CD (0.38) | GRM2KDRPIK3CDPIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709718-A1 | 6-SUBSTITUTED-3-PHENYL-ISOINDOLIN-1-ONES AS CBL-B INHIBITORS SELECTIVE OVER C-CBL | Genentech Inc. (US) | 2026-03-18 | — | — | EP | disclosed |