Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 3/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.30 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.30 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.30 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32686542 | 0.87 | PIK3CD (0.36) | PIK3CDPIK3CAPIK3CBGRM2 | |
| SCHEMBL27085830 | 0.81 | ALDH1A1 (0.42) | PIK3CDPIK3CAPIK3CBPIM1 | |
| SCHEMBL29920437 | 0.81 | ALDH1A1 (0.42) | PIK3CDPIK3CAPIK3CBPIM1 | |
| SCHEMBL32686271 | 0.80 | GRM2 (0.33) | GRM2PIM1CSNK1A1CDK5ROCK1 | |
| SCHEMBL32686378 | 0.79 | PIM1 (0.38) | PIK3CDPIK3CAPIK3CBGRM2PIM1 | |
| SCHEMBL30605858 | 0.78 | GRM2 (0.38) | PIK3CDPIK3CAPIK3CBGRM2PIM1 | |
| SCHEMBL30004086 | 0.77 | GRM2 (0.42) | PIK3CDPIK3CAPIK3CBGRM2PIM1 | |
| SCHEMBL27086356 | 0.77 | GRM2 (0.42) | PIK3CDPIK3CAPIK3CBGRM2PIM1 | |
| SCHEMBL32686609 | 0.76 | PIK3CD (0.38) | PIK3CDPIK3CAPIK3CBGRM2 | |
| SCHEMBL32686478 | 0.75 | ALDH1A1 (0.37) | PIK3CDPIK3CAPIK3CBGRM2PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709718-A1 | 6-SUBSTITUTED-3-PHENYL-ISOINDOLIN-1-ONES AS CBL-B INHIBITORS SELECTIVE OVER C-CBL | Genentech Inc. (US) | 2026-03-18 | — | — | EP | disclosed |