SCHEMBL32687035

SCHEMBL32687035

CCO[C@@H]1[C@@H](O)CN[C@@H]1Cc1ccc(-c2ccc3c(cnn3C)c2)cn1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CCNC P24863 2/20 0.35
▸ CDK8 P49336 2/20 0.35
▸ USP7 Q93009 1/20 0.35
▸ WNT1 P04628 1/20 0.35
▸ CLK2 P49760 1/20 0.35
▸ CLK3 P49761 1/20 0.35
▸ GSK3B P49841 1/20 0.35
▸ DYRK1A Q13627 1/20 0.35
▸ PRMT5 O14744 1/20 0.34
▸ FASN P49327 2/20 0.33
▸ LRRK2 Q5S007 1/20 0.33
▸ KDM1A O60341 1/20 0.33
▸ FLT3 P36888 1/20 0.33
▸ SYK P43405 1/20 0.33
▸ FAAH O00519 1/20 0.33
▸ KDM2B Q8NHM5 1/20 0.33
▸ CYP11B2 P19099 1/20 0.33
▸ BRD4 O60885 1/20 0.33
▸ CREBBP Q92793 1/20 0.33
▸ GBA1 P04062 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32687049 0.89 BCHE (0.46) PRMT5FAAHTRPA1BCHEESR1
SCHEMBL32687536 0.88 CYP2D6 (0.39) CCNCCDK8USP7WNT1CLK2
SCHEMBL32687507 0.81 ERCC1 (0.40) GSK3BFASNFLT3SYKBRD4
SCHEMBL32687201 0.77 SIGMAR1 (0.37) PRMT5TRPA1CTSCBCHE
SCHEMBL32687222 0.77 BCHE (0.42) FASNCTSCBCHE
SCHEMBL32687150 0.76 CYP2D6 (0.40) CCNCCDK8CTSC
SCHEMBL32687707 0.76 WNT1 (0.37) WNT1CLK2CLK3GSK3BDYRK1A
SCHEMBL32687195 0.76 CTSC (0.35) WNT1CLK2CLK3GSK3BDYRK1A
SCHEMBL32687373 0.76 CYP2D6 (0.39) CCNCCDK8FASNCTSC
SCHEMBL32687276 0.70 CYP2D6 (0.42) GBA1BCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260109696-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2026-04-23 — — US disclosed
US-20260078116-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2026-03-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260078116-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS MYC, KRAS, MCL1 CCNC 85/4885CDK8 540/4885USP7 2332/4885
US-20260109696-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS KRAS, MYC, NRAS CCNC 65/4885CDK8 230/4885USP7 2228/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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